208983-72-6Relevant academic research and scientific papers
Synthesis and biological evaluation of a water soluble phosphate prodrug of 3-aminopyridine-2-carboxaldehyde thiosemicarbazone (3-AP)
Li, Jun,Luo, Xiang,Wang, Qin,Zheng, Li-Mou,King,Doyle, Terrence W.,Chen, Shu-Hui
, p. 3159 - 3164 (1998)
With the aim of improving its biological and pharmaceutical profiles, two water soluble phosphate prodrugs of 3-AP, 3a and 3b were prepared. The detailed synthesis and the preliminary evaluation of these prodrugs are described.
Multiplex detection of enzymatic activity with responsive lanthanide-based luminescent probes
Pershagen, Elias,Borbas, K. Eszter
, p. 1787 - 1790 (2015/02/19)
Multiplex analyte detection in complex dynamic systems is desirable for the investigation of cellular communication networks as well as in medical diagnostics. A family of lanthanide-based responsive luminescent probes for multiplex detection is reported. The high modularity of the probe design enabled the rapid assembly of both green and red emitters for a large variety of analytes by the simple exchange of the lanthanide or an analyte-cleavable caging group, respectively. The real-time three-color detection of up to three analytes was demonstrated, thus setting the stage for the non-invasive investigation of interconnected biological processes. © 2015 Wiley-VCH Verlag GmbH & Co. KGaA , Weinheim.
