20904-31-8Relevant academic research and scientific papers
CONFORMATION OF DIARYL SULPHIDES WITH INTRAMOLECULAR SULPHUR(II)-OXYGEN INTERACTION: AN X-RAY STUDY OF METHYL 2-(4-NITROPHENYLTHIO)BENZOATE AND 2-DIAZOACETYL-4'-NITRODIPHENYL SULPHIDE
Kucsman, A.,Kapovits, I.,Parkanyi, L.,Kalman, A.
, p. 141 - 150 (1986)
The molecular structures of methyl 2-(4-nitrophenylthio)benzoate and 2-diazoacetyl-4'-nitrodiphenyl sulphide have been determined by X-ray diffraction.The skew conformation observed for the ester is favourable to the formation of a sulphur(II)-oxigen(carb
Coupling of thiols and aromatic halides promoted by diboron derived super electron donors
Franco, Mario,Vargas, Emily L.,Tortosa, Mariola,Cid
supporting information, p. 11653 - 11656 (2021/11/12)
We have proven that pyridine-boryl complexes can be used as superelectron donors to promote the coupling of thiols and aromatic halides through a SRN1 mechanism. The reaction is efficient for a broad substrate scope, tolerating heterocycles including pyridines, enolizable or reducible functional groups. The method has been applied to intermediates in drug synthesis as well as interesting functionalized polythioethers through a controlled and consecutive intramolecular electron transfer process.
Synthesis and structure-activity relationship studies of hiv-1 virion infectivity factor (vif) inhibitors that block viral replication
Ali, Akbar,Wang, Jinhua,Nathans, Robin S.,Cao, Hong,Sharova, Natalia,Stevenson, Mario,Rana, Tariq M.
experimental part, p. 1217 - 1229 (2012/07/17)
The human immunodeficiency virus1 (HIV-1) virion infectivity factor (Vif) protein, essential for in vivo viral replication, protects the virus from innate antiviral cellular factor apolipoproteinB mRNA-editing, enzyme-catalytic, polypeptide-like3G (APOBEC
Composition and synthesis of new reagents for inhibition of HIV replication
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Page/Page column 16; 27; 28, (2008/06/13)
The present invention provides compounds and compositions for inhibiting Vif and methods for treating viral infection, e.g., HIV infection.
