209049-98-9

Upstream product

• 14294-10-1 morpholinothiourea 
• 209049-88-7 5-chloroacetyl-2-morpholino-4-phenylthiazole 
• 40398-30-9 N-(morpholinothiocarbonyl)benzamide 

Downstream Products

• 209050-03-3 5-[5-formyl-2-(4-morpholino)-4-thiazolyl]-2-(4-morpholino)-4-phenylthiazole 
• 209050-06-6 2-(4-morpholino)-5-[2-(4-morpholino)-5-(2,2-dicyanovinyl-4-thiazolyl)]-4-phenyl-thiazole 

Relevant academic research and scientific papers

Synthesis and solvatochromic properties of 5-dicyanovinyl- and 5-tricyanovinyl-substituted 2-amino-thiazoles and 2-amino-thiophenes

Starting from 2-morpholinothiazoles 6 and 2-morpholinothiophenes 7 and following known routes several 5-dicyanovinyl and 5-tricyanovinyl-substituted derivatives 10 - 13 have been prepared and their solvatochromic properties estimated.

Preparation and properties of 2-dialkylamino-5-haloacetyl-thiazoles and 4-(2-dialkylamino-5-thiazolyl)-thiazoles

By the reaction of N-acylthioureas 7 with 1,3-dichloroacetone9 2-dialkylamino-5-chloroacetyl-thiazoles 11 are avialable. These compounds react with thioureas or arylthioamides under heterocyclisation to give bis-(2-dialkylamino-5-thiazolyl)-ketones 13, 2-aryl-4-(2-dialkylamino-5-thiazolyl)-thiazoles 14, or 2-dialkylamino-4-(2-dialkylamino-5-thiazolyl)-thiazoles 15, resp., from which the last-mentioned compound exhibit a high reactivity towards several electrophilic reagents. Thus, deeply colored cyanovinyl, arylazo, and arylmethine substituted bisthiazole dyes 17, 18, and 19, resp., have been formed. Johann Ambrosius Barth 1998.