168416-37-3

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 168610-03-5 methyl 2-hydroxy-2-methyl-3-phenyl-3-(1-phenylethylamino)propanoate 
• 357615-92-0 (2R,3S)-3-azido-2-hydroxy-2-methyl-3-phenylpropionic acid methyl ester 
• 124-41-4 sodium methylate 
• 100-52-7 benzaldehyde 
• 3129-98-4 (R)-benzylidene-(1-phenylethyl)amine 
• 209110-50-9 (3R,4S)-3-(Dimethyl-phenyl-silanyloxy)-1-(4-methoxy-phenyl)-4-phenyl-azetidin-2-one 
• 209110-55-4 (3R,4S)-3-(Dimethyl-phenyl-silanyloxy)-1-(4-methoxy-phenyl)-3-methyl-4-phenyl-azetidin-2-one 
• 209110-60-1 (3R,4S)-3-dimethylphenylsilyloxy-3-methyl-4-phenyl-β-lactam 
• 144465-78-1 1-(4-Methoxyphenyl)-3-triisopropylsilyloxy-4-phenyl-2-azetidinone 
• 357615-98-6 (2S,5R,1'S)-1'-(azidophenylmethyl)-2-tert-butyl-2,5-dimethyl-[1,3]-dioxolan-4-one 
• 313673-02-8 (2S,5R,1'R)-2-(tert-Butyl)-5-(1'-hydroxy-1'-phenylmethyl)-2,5-diethyl-1,3-dioxolan-4-one 
• 150884-50-7 benzaldehyde N-boc imine 
• 67-56-1 methanol 

Downstream Products

• 168610-05-7 C₅₀H₅₇Cl₆NO₁₈ 

Relevant academic research and scientific papers

Synthesis of optically active constrained 2-substituted norstatines: A straightforward application of Seebach's "SRS" synthetic principle

A straightforward two-step methodology of synthesis of optically active (2R)-substituted norstatines via addition of N-teri-butoxycarbonyl-substituted aldimines to (2S)-chiral enolates of 1,3-dioxolan-4-ones has been developed. In particular, the use of t

1′-Azido- and 1′-amino-1,3-dioxolan-4-ones

1,3-Dioxolanone alcohols, prepared via the addition of chiral lithium enolates of 1,3-dioxolan-4-ones to aldehydes, are suitable intermediates for the synthesis of chiral trisubstituted isoserines or trisubstituted 3-hydroxy-β-lactams. In particular, the

Extremely stereoselective alkylation of 3-siloxy-β-lactams and its applications to the asymmetric syntheses of novel 2-alkylisoserines, their dipeptides, and taxoids

New and efficient synthetic mutes to 2-alkylisoserines, their dipeptides and 2'-alkyl-taxoids were synthesized from enantiopure 3-alkyl-β-lactams 3 which were obtained through extremely distereoselective alkylation of β- lactams 2.

Docetaxel (Taxotere) derivatives: novel NbCl3-based stereoselective approach to 2'-methyldocetaxel

The C-2 methylated 2S,3R and 2R,3S side chains of docetaxel have been enantioselectively prepared and esterified with protected 10-deacetylbaccatin III to provide novel analogues of docetaxel.