209115-32-2

Basic information

• Product Name: 4-(FMOC-AMINO)-1-BUTANOL
• Synonyms: FMOC-NH-(CH2)4-OH;FMOC-ABU(4)-OL;FMOC-4-AMINOBUTANOL;4-(FMOC-AMINO)-1-BUTANOL;(9H-FLUOREN-9-YL)METHYL N-(4-HYDROXYBUTYL)CARBAMATE;AKOS 91345;N-(9-FLUORENYLMETHOXYCARBONYL)-DELTA-AMINO-N-BUTYL ALCOHOL;N-(9-FLUORENYLMETHOXYCARBONYL)-4-AMINO-1-BUTANOL
• CAS NO: 209115-32-2
• Molecular Formula: C₁₉H₂₁NO₃
• Molecular Weight: 311.37
• Mol File: 209115-32-2.mol
• Article Data: 6

Chemical Properties

• Melting Point: 113-118 °C
• Boiling Point: 521.7°Cat760mmHg
• Flash Point: 269.3°C
• Appearance: /
• Density: 1.189g/cm³
• Vapor Pressure: 1.03E-11mmHg at 25°C
• Refractive Index: 1.591
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 4-(FMOC-AMINO)-1-BUTANOL(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(FMOC-AMINO)-1-BUTANOL(209115-32-2)
• EPA Substance Registry System: 4-(FMOC-AMINO)-1-BUTANOL(209115-32-2)

Safety Data

• Hazard Codes: Xi
• WGK Germany: 3
• Hazardous Substances Data: 209115-32-2(Hazardous Substances Data)

Usage

General Description

4-(FMOC-AMINO)-1-BUTANOL, also known as Fmoc-amino alcohol, is a chemical compound commonly used in the field of organic chemistry and biochemistry. It is a derivative of butanol with an amino group and a 9-fluorenylmethyloxycarbonyl (Fmoc) protecting group attached to the nitrogen atom. 4-(FMOC-AMINO)-1-BUTANOL is commonly used as a building block for the synthesis of peptides and proteins, as well as in the preparation of solid-phase peptide synthesis reagents. Fmoc-amino alcohol is a versatile reagent that can be used in various chemical reactions, making it a valuable tool for researchers in the field of chemical and biomedical sciences.

InChI:InChI=1/C19H21NO3/c21-12-6-5-11-20-19(22)23-13-18-16-9-3-1-7-14(16)15-8-2-4-10-17(15)18/h1-4,7-10,18,21H,5-6,11-13H2,(H,20,22)

Upstream product

• 13325-10-5 4-Aminobutanol 
• 28920-43-6 (fluorenylmethoxy)carbonyl chloride 
• 82911-69-1 N-(9H-fluoren-2-ylmethoxycarbonyloxy)succinimide 

Downstream Products

• 1231608-91-5 [(2S,3S,4S,5R,6R)-4,5-diacetoxy-6-(acetoxymethyl)-2-[4-(9H-fluoren-9-ylmethoxycarbonylamino)butoxy]tetrahydropyran-3-yl] acetate 
• 115976-91-5 Philanthotoxin 433 

Relevant articles and documents

PHARMACEUTICAL COMPOSITION FOR RESPIRATORY ADMINISTRATION

The present invention provides a pharmaceutical composition for respiratory administration containing a polysaccharide derivative having a group derived from a polysaccharide and a group derived from a physiologically active substance that is covalently b

A versatile annulation protocol toward novel constrained phosphinic peptidomimetics

(Chemical Equation Presented) The development of a novel 3-center 2-component annulation reaction between α,ω-carbamoylaldehydes and suitably monoalkylated phosphinic acids is reported. Depending on the starting α,ω-carbamoylaldehyde, diverse phosphinic scaffolds varying in the size of their rigidity element, the nature and stereochemistry of substituents, and the participation of heteroatoms in the azacyclic ring system can be obtained in one synthetic step and in high yield. In addition, this methodology allows the synthesis of Fmoc-protected constrained aminophosphinic acids that can be easily converted to suitable pseudodipeptide building blocks compatible with the requirements of peptide synthesis on the solid phase. Finally, the careful choice of both substituents and protecting groups can provide functionally diverse, orthogonally protected constrained scaffolds for extended derivatization of the target phosphinic peptidomimetic structrures.

New nonnucleoside substrates for terminal deoxynucleotidyl transferase: Synthesis and dependence of substrate properties on structure

N-(9-Fluorenylmethoxycarbonyl)-ω-aminoalkyl-, N-(9- fluorenylmethoxycarbonyl)-8-amino-3,6-dioxaoctyl, and N-[(9- fluorenylmethoxycarbonyl)-6-aminohexanoyl]-2-aminoethyl triphosphates were synthesized. All of them were shown to be the substrates of the cal