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(R)-1-[(4S,5S)-5-((R)-1-Amino-2-phenyl-ethyl)-2,2-dimethyl-[1,3]dioxolan-4-yl]-heptylamine is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

209161-36-4

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209161-36-4 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 209161-36-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,0,9,1,6 and 1 respectively; the second part has 2 digits, 3 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 209161-36:
(8*2)+(7*0)+(6*9)+(5*1)+(4*6)+(3*1)+(2*3)+(1*6)=114
114 % 10 = 4
So 209161-36-4 is a valid CAS Registry Number.

209161-36-4Downstream Products

209161-36-4Relevant academic research and scientific papers

The synthesis of symmetrical and unsymmetrical P1/P1' cyclic ureas as HIV protease inhibitors

Patel, Mona,Kaltenbach III, Robert F.,Nugiel, David A.,McHugh Jr., Robert J.,Jadhav, Prabhakar K.,Bacheler, Lee T.,Cordova, Beverly C.,Klabe, Ronald M.,Erickson-Viitanen, Susan,Garber, Sena,Reid, Carol,Seitz, Steven P.

, p. 1077 - 1082 (1998)

Cyclic urea SD 146, a potent HIV protease inhibitor bearing a flat resistance profile, possessed poor solubility and bioavailability, which precluded further development of the compound. In an effort to improve upon the pharmacokinetic profile of the compound, several analogs modified at the P1/P1' residues were prepared and evaluated. Several of those compounds displayed significant improvement of physical properties.

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