209161-43-3Relevant academic research and scientific papers
The asymmetric reduction of imidazolinones with trichlorosilane
Wagner, Christian,Kotthaus, Andreas F.,Kirsch, Stefan F.
, p. 4513 - 4516 (2017)
It is shown how imidazolinones are reduced by trichlorosilane in a highly enantioselective fashion when treated with a novel Lewis base organocatalyst that is based on a 2,2′-bispyrrolidine core. Under mild reaction conditions and with low catalyst loading the hydrosilylation reaction provides a broad range of chiral imidazolidinones with various structural motifs including sterically demanding substituents, alkyls and aryls.
Influence des ultrasons sur la diastereoselectivite. Synthese d'imidazolidine-4-one chirales
Hubert, Cathy,Garrigues, Bernard
, p. 234 - 237 (2007/10/03)
A three-step synthesis of imidazolidine-4-one has been realized.Sodium dithionite was a very efficient reagent for the last step, the reduction of a ketone.The reaction is slow under the normal conditions of heating and its diastereoselectivity is poor.Un
