209286-96-4

Usage

Uses

Used in Organic Synthesis:
2-Iodo-3-nitropyridine is used as a building block in organic synthesis for the creation of various compounds. Its presence in the synthesis process is crucial for the formation of complex organic molecules that are used in a wide range of applications.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, 2-Iodo-3-nitropyridine is utilized as a key component in the production of pharmaceuticals. Its unique chemical properties make it a valuable asset in the development of new drugs and therapeutic agents.
Used in Agrochemicals Production:
2-Iodo-3-nitropyridine is also employed in the manufacture of agrochemicals, which are essential for the agricultural industry. Its role in this sector is to contribute to the development of products that enhance crop protection and yield.
Used in Dyes and Pigments Industry:
Furthermore, 2-Iodo-3-nitropyridine is used in the production of dyes and pigments, where its color-producing properties are harnessed to create a variety of colorants for different industries, including textiles, plastics, and printing inks.

Upstream product

• 4214-75-9 2-amino-3-nitropyridine 

Downstream Products

• 947330-58-7 3-nitro-2-(phenylethynyl)pyridine 
• 209798-50-5 (E)-2-styrylpyridin-3-amine 
• 209286-97-5 3-amino-2-iodopyridine 

Relevant academic research and scientific papers

Efficient one-pot transformation of aminoarenes to haloarenes using halodimethylisulfonium halides generated in situ

Halodimethylsulfonium halide 1, which is readily formed in situ from hydrohaloic acid and DMSO, is a good nucleophilic halide. This activated nucleophilic halide rapidly converts aryldiazonium salt prepared in situ by the same hydrohaloic acid and nitrite ion to aryl chlorides, bromides, or iodides in good yield. The combined action of nitrite ion and hydrohaloic acid in DMSO is required for the direct transformation of aromatic amines, which results in the production of aryl halides within 1 h. Substituted compounds with electron-donating or -withdrawing groups or sterically hindered aromatic amines are also smoothly transformed to the corresponding aromatic halides. The only observed by-product is the deaminated arene (usually 7%). The isolated aryldiazonium salts can also be converted to the corresponding aryl halides using 1. The present method offers a facile, one-step procedure for transforming aminoarenes to haloarenes and lacks the environmental pollutants that usually accompany the Sandmeyer reaction using copper halides.

Synthesis of functionalized nitroarylmagnesium halides via an iodine-magnesium exchange

(Chemical Equation Presented) Various nitro-substituted aryl and heteroaryl iodides undergo an iodine-magnesium exchange reaction when treated with PhMgCl leading to nitro-containing magnesium organometallics. These Grignard reagents display an excellent stability at temperatures below -40°C and do not undergo electron-transfer reactions. They react as expected with various electrophiles.

Sulfonic acid sulfonylamino n-(heteroaralkyl)-azaheterocyclylamide compounds

The compounds of formula I herein exhibit useful pharmacological activity and accordingly are incorporated into pharmaceutical compositions and used in the treatment of patients suffering from certain medical disorders. More specifically, they are inhibitors of the activity of Factor Xa. The present invention is directed to compounds of formula I, compositions containing compounds of formula I, and their use, for treating a patient suffering from, or subject to, a physiological condition which can be ameliorated by the administration of an inhibitor of the activity of Factor Xa.