947330-58-7

Basic information

• Product Name: 3-Nitro-2-(phenylethynyl)pyridine
• Synonyms: pyridine, 3-nitro-2-(2-phenylethynyl)-
• CAS NO: 947330-58-7
• Molecular Formula: C₁₃H₈N₂O₂
• Molecular Weight: 224.21
• Mol File: 947330-58-7.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 399.7°C at 760 mmHg
• Flash Point: 195.5°C
• Density: 1.3g/cm³
• Vapor Pressure: 3.09E-06mmHg at 25°C
• Refractive Index: 1.651
• CAS DataBase Reference: 3-Nitro-2-(phenylethynyl)pyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Nitro-2-(phenylethynyl)pyridine(947330-58-7)
• EPA Substance Registry System: 3-Nitro-2-(phenylethynyl)pyridine(947330-58-7)

Safety Data

• Hazardous Substances Data: 947330-58-7(Hazardous Substances Data)

Usage

General Description

3-Nitro-2-(phenylethynyl)pyridine is a chemical compound with the molecular formula C12H7N3O2. It is a nitro-substituted pyridine derivative containing a phenylethynyl group, which is a common structural motif in organic chemistry. 3-Nitro-2-(phenylethynyl)pyridine is known for its potential use as a building block in the synthesis of various organic materials, particularly in the field of materials science. It has also been studied for its potential biological activities, such as its possible use as a pharmaceutical intermediate or as a precursor for the synthesis of biologically active molecules. Additionally, 3-Nitro-2-(phenylethynyl)pyridine is known for its strong light absorption properties in the UV-visible region, making it a candidate for use in photonic and optoelectronic applications.

Upstream product

• 536-74-3 phenylacetylene 
• 209286-96-4 2-iodo-3-nitropyridine 
• 5470-18-8 2-Chloro-3-nitropyridine 

Downstream Products

• 288254-71-7 2-(phenyethynyl)-3-pyridinylamine 
• 1378237-42-3 2-phenyl-3H-pyrrolo[3,2-b]pyridin-3-one 1-oxide 
• 209798-50-5 (E)-2-styrylpyridin-3-amine 
• 25797-03-9 2-phenyl-1H-pyrrolo[3,2-b]pyridine 

Relevant articles and documents

Synthesis of 6-R-isoxazolo[4,3-b]pyridines and their reactions with C-nucleophiles

Available 2-chloro-3-nitropyridines were used to synthesize new representatives of 6-substituted 3-benzoylisoxazolo[4,3-b]pyridines, which were found to react with neutral C-nucleophiles to give 1,4-addition products.

Gold(i)-catalyzed synthesis of 2-substituted indoles from 2-alkynylnitroarenes with diboron as reductant

An efficient method for the synthesis of 2-substituted indoles via a diboron/base promoted tandem reductive cyclization of o-alkynylnitroarene under Au catalysis conditions has been disclosed. This reaction is efficient and convenient, affording 2-substituted indoles with broad functional groups tolerance and excellent yields.

Facile synthesis of 2-substituted 4-azaindoles

A novel and efficient strategy for the synthesis of 2-substituted 4-azaindoles from 2-chloro-3-nitropyridine through Pd-catalyzed Sonogashira cross-coupling, followed by reduction and heteroannulation on t-BuOK, is reported. Copyright Taylor & Francis Group, LLC.