209627-01-0Relevant academic research and scientific papers
Controlled monohalogenation of phosphonates: A new route to pure α- monohalogenated diethyl benzylphosphonates
Iorga, Bogdan,Eymery, Frederic,Savignac, Philippe
, p. 2671 - 2686 (2007/10/03)
Starting from diethyl benzylphosphonates, a wide variety of diethyl α- monofluoro, chloro, bromo and iodobenzylphosphonates have been obtained in pure form by a one-pot procedure. This high yielding method implies the intermediate protection of the benzyl anion with TMSCI followed by halogenation with an electrophilic halogenating reagent.
A highly selective synthesis of α-monofluoro- and α-monochloro- benzylphosphonates using eiectrophilic halogenation of benzylphosphonates carbanions
Iorga, Bogdan,Eymery, Frederic,Savignac, Philippe
, p. 3693 - 3696 (2007/10/03)
The selective electrophilic monofluorination and monochlorination of a wide variety of diethyl benzylphosphonates have been realized in a one-pot procedure. The monohalogenation was accomplished by intermediate of a benzylic carbanion protected with TMSCl
