209680-91-1 Usage
Uses
Used in Pharmaceutical Research and Development:
N-(tert-butyloxycarbonyl)-3-fluorophenylglycine is used as a building block in the synthesis of pharmaceuticals for its ability to contribute to the molecular structure and properties of the target compounds. The presence of the fluorine atom and the protecting group allows for the creation of diverse drug candidates with potentially improved pharmacokinetic and pharmacodynamic profiles.
Used in Organic Synthesis:
In the field of organic synthesis, N-(tert-butyloxycarbonyl)-3-fluorophenylglycine is employed as a versatile intermediate. Its unique structure allows for further chemical modifications and functionalization, facilitating the development of complex organic molecules and advanced materials.
Used in Medicinal Chemistry:
N-(tert-butyloxycarbonyl)-3-fluorophenylglycine is utilized in medicinal chemistry as a key component in the design and synthesis of novel bioactive molecules. Its incorporation into drug candidates can lead to the discovery of new therapeutic agents with enhanced efficacy and selectivity.
Used in Drug Discovery:
N-(tert-butyloxycarbonyl)-3-fluorophenylglycine is used as a starting material in drug discovery processes, where its chemical properties can be leveraged to create new pharmaceutical entities. N-(tert-butyloxycarbonyl)-3-fluorophenylglycine's structural features make it a promising candidate for the development of innovative treatments for various diseases and conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 209680-91-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,0,9,6,8 and 0 respectively; the second part has 2 digits, 9 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 209680-91:
(8*2)+(7*0)+(6*9)+(5*6)+(4*8)+(3*0)+(2*9)+(1*1)=151
151 % 10 = 1
So 209680-91-1 is a valid CAS Registry Number.
209680-91-1Relevant academic research and scientific papers
Rapid access to N-Boc phenylglycine derivatives via benzylic lithiation reactions
Barberis, Claude,Voyer, Normand,Roby, Johanne,Chénard, Sylvain,Tremblay, Martin,Labrie, Philippe
, p. 2965 - 2972 (2007/10/03)
We report a novel and efficient method for the enantioselective synthesis of N-Boc protected phenylglycines. Yields and enantiomeric ratios vary widely depending on the nature of the solvent, the substrate and on the method of forming the chiral complex. Results show that the major reaction pathway is an enantioselective deprotonation/substitution process. The enantioselectivity appears to be limited by the chiral discrimination ability of the s-BuLi-(-)-sparteine complex. The synthetic method described is one of the shortest route to useful enantioenriched N-Boc phenylglycine derivatives.
