209807-52-3

Upstream product

• 58287-77-7 N,N-diethyl-4-formylbenzamide 
• 36282-40-3 (3-methoxyphenyl)magnesium bromide 
• 186094-06-4 (±)-4-[hydroxy-(3-methoxyphenyl)methyl]-N,N-diethylbenzamide 
• 619-66-9 4-Carboxybenzaldehyde 
• 3612-20-2 1-phenylmethyl-4-piperidone 
• 156727-77-4 N,N-diethyl-4-(3-methoxybenzoyl)benzamide 

Downstream Products

• 256504-46-8 4-[(4-piperidinyl)-3-methoxybenzyl]-N,N-diethylbenzamide 
• 209807-51-2 N,N-diethyl-4-(3-methoxyphenyl-piperidin-4-ylidene-methyl)-benzamide 

Relevant academic research and scientific papers

Compounds with analgesic effect

Compounds of general formula (I) are disclosed and claimed in the present application, as well as their pharmaceutically acceptable salts, pharmaceutical compositions comprising the novel compounds and their use in therapy, in particular in the management of pain.

Probes for narcotic receptor mediated phenomena. 26. Synthesis and biological evaluation of diarylmethylpiperazines and diarylmethylpiperidines as novel, nonpeptidic δ opioid receptor ligands

We recently reported (+)-4-[(αR)-α-{(2S,5R)-4-allyl-2,5- dimethyl-1-piperazinyl}-3-methoxybenzyl]-N,N-diethylbenzamide (1b, SNC80) as a novel nonpeptidic δ receptor agonist and explored the structure-activity relationships (SAR) of a series of related der