209859-22-3Relevant academic research and scientific papers
Carbene-Catalyzed Enantioselective Hydrophosphination of α-Bromoenals to Prepare Phosphine-Containing Chiral Molecules
Chai, Huifang,Chi, Yonggui Robin,Jin, Zhichao,Maiti, Rakesh,Mondal, Bivas,Xu, Jun,Yan, Jia-Lei,Yang, Xing
supporting information, p. 26616 - 26621 (2021/11/10)
Disclosed herein is the first carbene-organocatalyzed asymmetric addition of phosphine nucleophiles to the in situ generated α,β-unsaturated acyl azolium intermediates. Our reaction enantioselectively constructs carbon–phosphine bonds and prepares chiral
Highly asymmetric NHC-catalyzed hydroacylation of unactivated alkenes
Piel, Isabel,Steinmetz, Marc,Hirano, Keiichi,Froehlich, Roland,Grimme, Stefan,Glorius, Frank
, p. 4983 - 4987 (2011/06/21)
NHC-catalysis proto(n)type: The title reaction produces 21 different chroman-4-one-type products in good yields and excellent enantioselectivities, in each case building up a new all-carbon quaternary stereocenter (see scheme). Based on DFT calculations a
Comparison of chiral thiazolium and triazolium salts as asymmetric catalysts for the benzoin condensation
Knight, Roland L.,Leeper, Finian J.
, p. 1891 - 1893 (2007/10/03)
Chiral bicyclic 1,2,4-triazolium salts having a defined face of the heterocyclic ring hindered have been synthesised and they catalyse the benzoin condensation in good yield; the enantiomeric excesses obtained (up to 80%) are much better than with closely
