209910-45-2Relevant articles and documents
Nα-Fmoc-peptide azides: Synthesis, isolation, characterization and utility in the extension of peptide chains
Suresh Babu, Vommina V.,Vasanthakumar, Ganga-Ramu,Patil, Basanagoud S.
, p. 1853 - 1858 (2007/10/03)
Syntheses of Nα-Fmoc-peptide azides employing acid chloride as well as mixed anhydride methods have been carried out. The resulting Fmoc-peptide azides prepared have been isolated as solids in good yield (75-92 %) and are found to be analytical
Fmoc-peptide acid chlorides in fragment coupling: Synthesis of β- casomorphin by 3+2 divergent approach
Suresh Babu,Gayathri,Gopi
, p. 79 - 91 (2007/10/03)
Fmoc-peptide acid chlorides are prepared and used as rapid and efficient coupling agents in fragment coupling. Thus the synthesis of the model tetrapeptide Leu-Ala-Gly-Val and β-casomorhin (Tyr-Pro-Phe-Pro-Gly) are accomplished by the (2+2) and (3+2) divergent approach respectively.
Synthesis of peptides mediated by AgCN
Suresh Babu,Gayathri
, p. 1109 - 1113 (2007/10/03)
The acylation reactions employing Fmoc-amino acid chlorides have been carried out in the presence of AgCN. There is no addition of any base. The coupling is fast and racemization free. The work up and the isolation of products are easy. Thus the synthesis of several dipeptides, a model tetrapeptide, Leu-Ala-Gly-Val and β-casomorphin (Tyr-Pro-Phe-Pro-Gly) are accomplished.
Fmoc-peptide acid chlorides : Preparation, characterization and utility in peptide synthesis
Gayathri,Gopi,Suresh Babu
, p. 151 - 154 (2007/10/03)
Fmoc-protected peptide acid chlorides have been prepared as crystalline solids and characterized They are used as coupling agents for the synthesis of the model tetrapeptide, Leu-Ala-Gly-Val.
