221174-16-9

Basic information

• Product Name: Fmoc-Ala-Gly-Val-OBzl
• Synonyms: Fmoc-Ala-Gly-Val-OBzl
• CAS NO: 221174-16-9
• Molecular Weight: 557.646
• Mol File: 221174-16-9.mol

Chemical Properties

• CAS DataBase Reference: Fmoc-Ala-Gly-Val-OBzl(CAS DataBase Reference)
• NIST Chemistry Reference: Fmoc-Ala-Gly-Val-OBzl(221174-16-9)
• EPA Substance Registry System: Fmoc-Ala-Gly-Val-OBzl(221174-16-9)

Safety Data

• Hazardous Substances Data: 221174-16-9(Hazardous Substances Data)

Upstream product

• 21760-98-5 L-valine benzyl ester 
• 221174-14-7 Fmoc-Gly-Val-OBzl 
• 103321-50-2 9H-fluoren-9-ylmethyl [(1S)-2-chloro-1-methyl-oxoethyl]carbamate 
• 146117-53-5 H-Gly-Val-OBzl 

Downstream Products

• 221174-17-0 Ala-Gly-Val-OBzl 
• 209910-45-2 Fmoc-Leu-Ala-Gly-Val-OBzl 

Relevant articles and documents

Nα-Fmoc-peptide azides: Synthesis, isolation, characterization and utility in the extension of peptide chains

Syntheses of Nα-Fmoc-peptide azides employing acid chloride as well as mixed anhydride methods have been carried out. The resulting Fmoc-peptide azides prepared have been isolated as solids in good yield (75-92 %) and are found to be analytical

Synthesis of peptides mediated by AgCN

The acylation reactions employing Fmoc-amino acid chlorides have been carried out in the presence of AgCN. There is no addition of any base. The coupling is fast and racemization free. The work up and the isolation of products are easy. Thus the synthesis of several dipeptides, a model tetrapeptide, Leu-Ala-Gly-Val and β-casomorphin (Tyr-Pro-Phe-Pro-Gly) are accomplished.