209917-95-3

Basic information

• Product Name: 1-(3-cyanophenyl)-3-methylpyrazol-5-yl carboxylic acid chloride
• Synonyms: 1-(3-cyanophenyl)-3-methylpyrazol-5-yl carboxylic acid chloride
• CAS NO: 209917-95-3
• Molecular Weight: 245.668
• Mol File: 209917-95-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-(3-cyanophenyl)-3-methylpyrazol-5-yl carboxylic acid chloride(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(3-cyanophenyl)-3-methylpyrazol-5-yl carboxylic acid chloride(209917-95-3)
• EPA Substance Registry System: 1-(3-cyanophenyl)-3-methylpyrazol-5-yl carboxylic acid chloride(209917-95-3)

Safety Data

• Hazardous Substances Data: 209917-95-3(Hazardous Substances Data)

Upstream product

• 2881-99-4 3-cyano-phenylhydrazine hydrochloride 
• 209958-57-6 2-(3-cyano-phenyl)-5-methyl-2H-pyrazole-3-carboxylic acid ethyl ester 
• 82874-96-2 2-methoxyimino-4-oxo-pentaneperoxoic acid ethyl ester 

Downstream Products

• 209959-32-0 1-(3-cyanophenyl)-3-methyl-5-([5-(2'-methylsulfonylphenyl)pyrid-2-yl]aminocarbonyl)pyrazole 
• 209960-25-8 1-(3-cyanophenyl)-3-methyl-5-((3-fluoro-4-(N-morpholino)phenyl)aminocarbonyl)pyrazole 
• 256512-36-4 2-(3-cyano-phenyl)-5-methyl-2H-pyrazole-3-carboxylic acid (2'-tert-butylsulfamoyl-biphenyl-4-yl)-methyl-amide 
• 209958-59-8 1-(3-cyanophenyl)-N-[2'-(tert-butylaminosulfonyl) [1,1'-biphenyl]-4-yl]-3-methyl-1H-pyrazole-5-carboxamide 

Relevant articles and documents

Discovery of 1-[3-(Aminomethyl)phenyl]-N-[3-fluoro-2′-(methylsulfonyl)-[1,1′-b iphenyl]-4-yl]-3-(trifluoromethyl)-1H-pyrazole-5-carboxamide (DPC423), a highly potent, selective, and orally bioavailable inhibitor of blood coagulation factor Xa

Factor Xa (fXa) plays a critical role in the coagulation cascade, serving as the point of convergence of the intrinsic and extrinsic pathways. Together with nonenzymatic cofactor Va and Ca2+ on the phospholipid surface of platelets or endotheli