21021-53-4

Usage

Uses

Used in Pharmaceutical Synthesis:
4-Nitrophenylsuccinic acid is employed as a key intermediate in the synthesis of pharmaceuticals, contributing to the development of new drugs and therapeutic agents.
Used in Agrochemical Production:
4-NITROPHENYLSUCCINIC ACID is also utilized in the production of agrochemicals, playing a role in the creation of substances that help protect crops and enhance agricultural productivity.
Used in Dye Manufacturing:
4-Nitrophenylsuccinic acid is used in the manufacturing of dyes, contributing to the coloration and quality of various products in the textile and other industries.
Used in Enzyme Activity Studies:
As a substrate, 4-Nitrophenylsuccinic acid is instrumental in the study of enzyme activity and inhibition, aiding researchers in understanding enzymatic mechanisms and developing enzyme-targeted therapies.
Used in Research and Development:
In the scientific community, 4-Nitrophenylsuccinic acid is used in research and development for its reactivity and properties, enabling the exploration of new chemical reactions and applications.

InChI:InChI=1/C10H9NO6/c12-9(13)5-8(10(14)15)6-1-3-7(4-2-6)11(16)17/h1-4,8H,5H2,(H,12,13)(H,14,15)/p-2/t8-/m0/s1

Upstream product

• 635-51-8 2-phenylsuccinic acid 
• 91960-25-7 *2,3-Dicarbamoyl-3-<4-nitro-phenyl>-propionsaeure-aethylester 
• 7697-37-2 nitric acid 

Downstream Products

• 52174-44-4 3-(4-nitrophenyl)-2,5-dihydrofuran-2,5-dione 
• 33061-62-0 (4-Nitro-phenyl)-bernsteinsaeure-dimethylester 
• 92289-20-8 2-(4-Nitro-phenyl)-bernsteinsaeure-monomethylester-⁽⁴⁾ 
• 39243-36-2 dihydro-3-(4-nitrophenyl)furan-2.5-dione 
• 98953-18-5 3-(4-nitrophenyl)propionamide 
• 93534-72-6 2-(4-Nitro-phenyl)-bernsteinsaeure-monomethylester-⁽¹⁾ 
• 404034-30-6 diethyl 2-(4-nitrophenyl)succinate 
• 1383987-11-8 (2R,3S)-methyl 3-(4-nitrophenyl)-5-oxo-2-(thiophen-2-yl)tetrahydrofuran-3-carboxylate 

Relevant academic research and scientific papers

Catalytic Asymmetric γ-Lactam Synthesis from Enolisable Anhydrides and Imines

An anion-binding approach to the problem of preparing enantioenriched γ-lactams from enolisable anhydrides and imines is reported. A simple bisurea catalyst promotes the cycloaddition between α-aryl succinic anhydrides and either PMP- or benzhydryl-protec

The base-catalysed Tamura cycloaddition reaction: Calculation, mechanism, isolation of intermediates and asymmetric catalysis

A combined experimental and computational investigation has revealed that the base-catalysed Tamura cycloaddition between homophthalic anhydride and activated alkenes/alkynes-a reaction previously thought of as a Diels-Alder type process-proceeds via a stepwise mechanism involving conjugate addition and ring closure; which allowed the first catalytic asymmetric α-substitution reactions to be demonstrated with up to >99% ee.

Catalytic, enantio- and diastereoselective synthesis of γ-butyrolactones incorporating quaternary stereocentres

A new, highly enantio- and diastereoselective catalytic asymmetric formal cycloaddition of aryl succinic anhydrides and aldehydes which generates paraconic acid (γ-butyrolactone) derivatives is reported.

Methods for forming combinatorial libraries combining amide bond formation with epoxide opening

The invention relates to methods for forming combinatorial libraries. The invention provides methods suitable for the rapid and convenient synthesis of very large combinatorial libraries of small organic molecules. In particular, the invention provides a