210217-89-3

Upstream product

• 210217-82-6 4-nitrophenyl 2,3,4-tri-O-acetyl-6,7-dideoxy-β-D-galacto-hept-6-enopyranoside 
• 100-02-7 4-nitro-phenol 
• 210217-80-4 Acetic acid (2R,3R,4S,5S,6R)-3,5-diacetoxy-2-bromo-6-ethynyl-tetrahydro-pyran-4-yl ester 
• 210217-81-5 Acetic acid (2S,3R,4S,5S,6R)-4,5-diacetoxy-6-ethynyl-2-(4-nitro-phenoxy)-tetrahydro-pyran-3-yl ester 

Relevant academic research and scientific papers

Diastereoselective resolution of 6-substituted glycosides via enzymatic hydrolysis

The diastereoselectivity of the enzymatic hydrolyses of 4-nitrophenyl 6- deoxy-6-methyl(R)- and (S)-sulfinyl-β-D-galactopyranoside (1a,b), 4- nitrophenyl 7-deoxy-D- and L-glycero-β-D-galacto-heptopyranoside (2a,b) and 4-nitrophenyl 6,7-anhydro-D- and L-glycero-β-Dgalacto-heptopyranoside (3a,b) was investigated using a range of crude glycosidase preparations. It was shown that the enzymes display a high degree of discrimination between diastereomers thereby demonstrating the utility of glycosidases for the diastereomeric resolution of unnatural 6-substituted monosaccharide derivatives.