2103-95-9

Basic information

• Product Name: 37(4-BROMOPHENYL)-2-THIAZOLETHIOL
• Synonyms: 37(4-BROMOPHENYL)-2-THIAZOLETHIOL;4-(4-Bromophenyl)-2-thiazolethiol;(4-BROMOPHENYL)-2-THIAZOLETHIOL;4-(4-bromophenyl)thiazole-2-thiol;4-(4-bromophenyl)-3H-1,3-thiazole-2-thione
• CAS NO: 2103-95-9
• Molecular Formula: C₉H₆BrNS₂
• Molecular Weight: 272.18
• Product Categories: Heterocyclic Compounds;Building Blocks;Halogenated Heterocycles;Heterocyclic Building Blocks;Thiazoles;ThiazolesHeterocyclic Building Blocks
• Mol File: 2103-95-9.mol
• Article Data: 7

Chemical Properties

• Melting Point: 220-224 °C
• Boiling Point: 376.2°C at 760 mmHg
• Flash Point: 181.32°C
• Appearance: /
• Density: 1.768g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.783
• PKA: 7.66±0.40(Predicted)
• CAS DataBase Reference: 37(4-BROMOPHENYL)-2-THIAZOLETHIOL(CAS DataBase Reference)
• NIST Chemistry Reference: 37(4-BROMOPHENYL)-2-THIAZOLETHIOL(2103-95-9)
• EPA Substance Registry System: 37(4-BROMOPHENYL)-2-THIAZOLETHIOL(2103-95-9)

Safety Data

• Hazard Codes: Xn
• Statements: 22-37/38-41
• Safety Statements: 26-39
• RIDADR: UN 2811 6.1/PG 3
• WGK Germany: 3
• Hazardous Substances Data: 2103-95-9(Hazardous Substances Data)

Usage

General Description

The chemical 37(4-Bromophenyl)-2-thiazolethiol is a thiazole compound containing a 4-bromophenyl group. It is a sulfur-containing organic compound that is commonly used in the synthesis of pharmaceuticals and agrochemicals. 37(4-BROMOPHENYL)-2-THIAZOLETHIOL exhibits potential antioxidant and antimicrobial activities, making it a valuable building block for the development of new drug candidates. Additionally, its aromatic nature and thiazole sulfur moiety make it a versatile intermediate for the synthesis of various organic molecules. Overall, 37(4-Bromophenyl)-2-thiazolethiol is a versatile building block with potential applications in the pharmaceutical and agrochemical industries.

InChI:InChI=1/C9H6BrNS2/c10-7-3-1-6(2-4-7)8-5-13-9(12)11-8/h1-5H,(H,11,12)

Upstream product

• 99-73-0 para-bromophenacyl bromide 
• 513-74-6 ammonium dithiocarbamate 
• 98475-05-9 α-tosyloxy-4-bromoacetophenone 
• 99-90-1 para-bromoacetophenone 

Downstream Products

• 97755-70-9 4-(4-bromo-phenyl)-2-(4-chloro-phenyldisulfanyl)-thiazole 
• 2103-93-7 2-methylmercapto-4-(4'-bromophenyl)thiazole 
• 1392400-77-9 2-(3-propyl-1-phenyl-4,5-dihydro-5-oxopyrazol-4-thio)-4-(4-bromophenyl)thiazole 
• 1392400-76-8 2-(3-methyl-1-phenyl-4,5-dihydro-5-oxopyrazol-4-thio)-4-(4-bromophenyl)thiazole 
• 1392400-78-0 2-(1,3-diphenyl-4,5-dihydro-5-oxopyrazol-4-thio)-4-(4-bromophenyl)thiazole 
• 94210-37-4 4,4'-bis-(4-bromo-phenyl)-2,2'-disulfanediyl-bis-thiazole 
• 1571918-41-6 (Z)-N-((2R,3S,4R)-1-((4-(4-bromophenyl)thiazol-2-yl)thio)-3,4-isopropylidenedioxyoctadec an-2-yl)tetracos-15-enamide 
• 116626-10-9 2-[4-(4-Bromo-phenyl)-thiazol-2-ylsulfanylmethyl]-5-methylsulfanyl-[1,3,4]oxadiazole 
• 116626-07-4 5-[4-(4-Bromo-phenyl)-thiazol-2-ylsulfanylmethyl]-[1,3,4]oxadiazole-2-thiol 
• 116626-11-0 2-Methylsulfanyl-5-(4-phenyl-thiazol-2-ylsulfanylmethyl)-[1,3,4]oxadiazole 
• 116626-04-1 [4-(4-Bromo-phenyl)-thiazol-2-ylsulfanyl]-acetic acid hydrazide 
• 116626-03-0 [4-(4-Bromo-phenyl)-thiazol-2-ylsulfanyl]-acetic acid ethyl ester 
• 97236-61-8 4-(4-bromo-phenyl)-2-phenyldisulfanyl-thiazole 
• 97215-58-2 4-(4-bromo-phenyl)-2-(2-nitro-phenyldisulfanyl)-thiazole 

Relevant articles and documents

Synthesis of novel azabicyclo derivatives containing a thiazole moiety and their biological activity against pine-wood nematodes

To explore a new skeleton with nematicidal activity, a series of novel azabicyclo derivatives containing a thiazole moiety were designed, synthesized and evaluated for their nematicidal activities. The bioassay results against pine-wood nematodes (Bursaphelenchus xylophilus) showed that most of the title compounds displayed nematicidal activity at a concentration of 40 mg/L. Especially, the title compounds2-((8-methyl-8-azabicyclo[3.2.1]octan-3-yl)oxy)-4-(4-chlorophenyl)thiazole (7e), 2-((8-methyl-8-azabicyclo[3.2.1]octan-3-yl)thio)-4-phenylthiazole (10a) and 2-((8-methyl-8-azabicyclo [3.2.1]octan-3-yl)thio)-4-(4-chlorophenyl)thiazole (10e) exhibited more than 90% mortality against Bursaphelenchus xylophilus.

Synthesis new and novel aryl thiazole derivatives compounds

Six new compounds of Thiazoles family was synthesis from condensation reaction of some compounds from pyrazolines. NMR, IR and elemental analysis was used for identification of these compounds. Position of aliphatic and aromatic hydrogens in pyrazolone and thiazole cycles had established proceeding of identification. Most of obtained compounds like aciform crystals, their color is white and yellow. Reaction time and yield of these compounds had shown better results as compared with other thiazole derivations.

A facile synthesis of thiazole-2(3H)-thiones through [hydroxy(tosyloxy) iodo]benzene

A one-pot facile synthesis of thiazole-2(3H)-thiones (4) has been achieved by hypervalent iodine oxidation of ketones (1) using [hydroxy (tosyloxy)iodo]benzene, followed by the treatment of the reaction mixture with dithiocarbamate salts (3) The intermediate α-tosyloxy-ketones (2) have also been isolated and converted to the target compounds.