210416-82-3

Upstream product

• 210416-70-9 (Z)-1-Ethoxy-4,4-dimethyl-2-phenylsulfanyl-pent-1-en-3-ol 
• 630-19-3 pivalaldehyde 
• 59377-31-0 ((E)-2-Ethoxy-vinylsulfanyl)-benzene 

Downstream Products

• 210416-92-5 (1Z,4Z,6Z)-1-Ethoxy-8,8-dimethyl-2,4,6-tris-phenylsulfanyl-nona-1,4,6-trien-3-ol 
• 210416-91-4 6,6-dimethyl-2,4-bis(phenylthio)hepta-2,4-dienal 
• 210416-93-6 (2E,4E,6E)-8,8-dimethyl-2,4,6-tris(phenylthio)nona-2,4,6-trienal 
• 210416-90-3 (1Z,4Z)-1-Ethoxy-6,6-dimethyl-2,4-bis-phenylsulfanyl-hepta-1,4-dien-3-ol 

Relevant academic research and scientific papers

The First Example of the 1-Chalcogene-Substituted Formylolefination of the Ketones and Aldehydes Using 1-Lithio-2-ethoxyvinyl Chalcogenides

The α-chalcogene-substituted formylolefinations of ketones and aldehydes proceeded using 1-lithio-2-ethoxyvinyl chalcogenides/PPSE or TMSOTf to produce the α-chalcogenoformylolefinated products 4a-l in high yields. Tandem-formylolefmation provided the (2Z,4Z)-2,4-bis(chalcogeno)pent-2,4-dienals 5d,h,i and (2Z,4Z,6Z)-2,4,6-tris(phenylthio)hept-2,4,6-trienal derivatives 7d and 8d, respectively.