210532-73-3Relevant academic research and scientific papers
Synthesis of tokaramide A, a cysteine protease inhibitor from marine sponge Theonella aff. mirabilis
Konno, Hiroyuki,Nosaka, Kazuto,Akaji, Kenichi
experimental part, p. 9067 - 9071 (2011/12/01)
The first synthesis of tokaramide A (1) is described. Tokaramide A (1) was synthesized via the peptide with a side-chain unprotected arginine residue on Weinreb AM resin by reductive cleavage.
Total synthesis of miraziridine A and identification of its major reaction site for cathepsin B
Konno, Hiroyuki,Kubo, Kanako,Makabe, Hidefumi,Toshiro, Emi,Hinoda, Naoyuki,Nosaka, Kazuto,Akaji, Kenichi
, p. 9502 - 9513 (2008/02/12)
The synthesis of miraziridine A, a pentapeptide derivative isolated from marine sponge, and its truncated analogs has been achieved. To construct the backbone of miraziridine A, a side-chain-unprotected vinylogous arginine was condensed with an aziridine-
