210539-04-1

Basic information

• Product Name: 6-BENZYL-2-CHLORO-5,6,7,8-TETRAHYDRO-1,6-NAPHTHYRIDINE
• Synonyms: 6-BENZYL-2-CHLORO-5,6,7,8-TETRAHYDRO-1,6-NAPHTHYRIDINE;2-Chloro-5,6,7,8-tetrahydro-6-(phenylmethyl)-1,6-naphthyridine;6-benzyl-2-chloro-5,6,7,8-tetrahydro-1,6-naphthyridine hydrochloride
• CAS NO: 210539-04-1
• Molecular Formula: C₁₅H₁₅ClN₂
• Molecular Weight: 258.75
• Mol File: 210539-04-1.mol

Chemical Properties

• Boiling Point: 373.06 °C at 760 mmHg
• Flash Point: 179.421 °C
• Appearance: /
• Density: 1.227
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.621
• Storage Temp.: 2-8°C
• PKA: 5.70±0.20(Predicted)
• CAS DataBase Reference: 6-BENZYL-2-CHLORO-5,6,7,8-TETRAHYDRO-1,6-NAPHTHYRIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 6-BENZYL-2-CHLORO-5,6,7,8-TETRAHYDRO-1,6-NAPHTHYRIDINE(210539-04-1)
• EPA Substance Registry System: 6-BENZYL-2-CHLORO-5,6,7,8-TETRAHYDRO-1,6-NAPHTHYRIDINE(210539-04-1)

Safety Data

• Hazardous Substances Data: 210539-04-1(Hazardous Substances Data)

Usage

Uses

Used in Scientific Research:
6-Benzyl-2-chloro-5,6,7,8-tetrahydro-1,6-naphthyridine is used as a research compound for studying its chemical properties and potential applications in various fields. Its unique structure with a benzyl group and a chlorine atom may offer insights into the synthesis and reactivity of related compounds.
Used in Chemical Industries:
6-Benzyl-2-chloro-5,6,7,8-tetrahydro-1,6-naphthyridine is used as an intermediate in the synthesis of other organic compounds, particularly those with potential applications in pharmaceuticals or materials science. Its presence in the tetrahydro-1,6-naphthyridine group suggests that it may be a key component in the development of new drugs or materials with specific properties.

InChI:InChI=1/C15H15ClN2/c16-15-7-6-13-11-18(9-8-14(13)17-15)10-12-4-2-1-3-5-12/h1-7H,8-11H2

Upstream product

• 601514-58-3 6-benzyl-5,6,7,8-tetrahydro-[1,6]-naphthyridin-2(1H)-one 
• 935838-05-4 N-(1-benzyl-1,2,3,6-tetrahydro-pyridin-4-yl)-acetamide 
• 210539-03-0 6-benzyl-3,4,5,6,7,8-hexahydro-1,6-naphthyridin-2(1H)-one 
• 3612-20-2 1-phenylmethyl-4-piperidone 
• 16675-58-4 1-Benzyl-4-(1-pyrrolidinyl)-1,2,3,6-tetrahydro-pyridine 
• 100-39-0 benzyl bromide 
• 23616-29-7 1,6-naphthyridin-2(1H)-one 

Downstream Products

• 869640-28-8 6-benzyl-2-(3-pyrrolidin-1-yl-propoxy)-5,6,7,8-tetrahydro-1,6-naphthyridine 
• 676994-60-8 6-benzyl-2-methoxy-5,6,7,8-tetrahydro-[1,6]naphthyridine 
• 1151665-09-6 6-benzyl-N-isobutyl-5,6,7,8-tetrahydro-1,6-naphthyridin-2-amine 
• 601514-81-2 4-(6-benzyl-7,8-dihydro-5H-1,6-naphthyridin-2-yl)morpholine 
• 1151665-05-2 6-benzyl-2-pyrrolidin-1-yl-5,6,7,8-tetrahydro-1,6-naphthyridine 
• 1151665-28-9 6-benzyl-2-chloro-8-methyl-5,6,7,8-tetrahydro-1,6-naphthyridine 
• 1151665-06-3 6-benzyl-N,N-dimethyl-5,6,7,8-tetrahydro-1,6-naphthyridin-2-amine 
• 1151665-24-5 6-benzyl-2-(1-ethylpropyl)-5,6,7,8-tetrahydro-1,6-naphthyridine 
• 1151665-15-4 2-chloro-7,8-dihydro-5H-[1,6]naphthyridine-6-carboxylic acid tert-butyl ester 
• 1151665-26-7 6-benzyl-2-tert-butoxy-5,6,7,8-tetrahydro-1,6-naphthyridine 
• 1151665-14-3 6-benzyl-2-isopropyl-5,6,7,8-tetrahydro-1,6-naphthyridine 
• 1151665-07-4 6-benzyl-N-isopropyl-5,6,7,8-tetrahydro-1,6-naphthyridin-2-amine 
• 1151665-25-6 6-benzyl-2-cyclopropyl-5,6,7,8-tetrahydro-1,6-naphthyridine 
• 1151665-18-7 6-benzyl-2-(1-cyclopropylethoxy)-5,6,7,8-tetrahydro-1,6-naphthyridine 

Relevant articles and documents

Compounds and methods of use

Compounds are provided according to Formula (I): and pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof; wherein X1, X2, X3, X4, Y, A, L1, L2, R1, R2, R5, m and n are as defined herein. Compounds of the present invention are contemplated useful for the prevention and treatment of a variety of conditions.

Substituted amide compound and application

The invention belongs to the field of agricultural bactericidal, insecticidal and acaricidal agents, and relates to a substituted amide compound and an application. The substituted amide compound has a structure as shown in a general formula I in the specification; and in the general formula I, substituents are defined in the specification. The compound provided by the invention has broad-spectrum bactericidal, insecticidal and acaricidal activities, has excellent control effects on diseases like cucumber downy mildew, corn rust, wheat powdery mildew and rice blast, especially has better control effects on the corn rust, also has excellent control effects on aphids and Tetranychus cinnabarinus, and especially can obtain good effects on the Tetranychus cinnabarinus at a low dosage.

ANTI-PULMONARY TUBERCULOSIS NITROIMIDAZOLE DERIVATIVE

Disclosed is a substituted nitroimidazole derivative, which is mainly used for treating related diseases caused by mycobacterial infections, such as Mycobacterium tuberculosis, especially being suitable for diseases caused by resistant Mycobacterium tuberculosis.

Substituted tetrahydroisoquinoline compound and application

The invention discloses a substituted tetrahydroisoquinoline compound and application. The compound has a structure as shown in a general formula I in the specification; and in the general formula I, substituents are defined in the specification. The comp

CONDENSED PYRIDINE DERIVATIVE AND USE THEREOF

Provided are a condensed pyridine derivative having a serotonin 5-HT2C receptor activation action, a prophylactic or therapeutic agent for a lower urinary tract symptom, obesity and/or organ prolapse and the like containing the condensed pyridine derivative, a screening method for a substance that increases leak point pressure upon a rise in the intravesical pressure or a prophylactic or therapeutic drug for stress urinary incontinence, a prophylactic or therapeutic drug for cystoceles or enteroceles, containing a substance that activates serotonin 5-HT2C receptor, and a method of screening for a therapeutic drug for cystoceles or enteroceles, including increasing an intravesical pressure after bilateral transection of the hypogastric nerve and pudendal nerve of an animal, and measuring a closure response in the urethra, the rectum or the vagina observed at that time. A serotonin 5-HT2C receptor activator containing a compound represented by the formula: wherein each symbol is as defined in the specification, or a salt thereof.

TETRAHYDRONAPHTHYRIDINE DERIVATIVE

The invention relates to 6-[2-(1-Isopropyl-piperidin-4-yloxy)-7,8-dihydro-5H-[1 ,6]naphthyridin-6-yl]-nicotinamide of Formula (I) and to processes for the preparation of, compositions containing and the uses of, the compound. The compound is an H3 ligand and is useful in numerous diseases, disorders and conditions, in particular inflammatory, allergic and respiratory diseases, disorders and conditions.

Tetrahydronaphthyridine derivates useful as histamine H3 receptor ligands

The invention relates to tetrahydronaphthyridine derivatives having formula (I) and to processes for the preparation of, intermediates used in the preparation of, compositions containing and the uses of, such derivatives. Said tetrahydronaphthyridine derivatives are H3 ligands and are useful in numerous diseases, disorders and conditions, in particular inflammatory, allergic and respiratory diseases, disorders and conditions.

Quinoline and quinazoline compounds useful in therapy, particularly in the treatment of benign prostatic hyperplasia

Compounds of formula I, STR1whereinR 1 represents C 1-4 alkoxy optionally substituted by one or more fluorine atoms;R 2 represents H or C 1-6 alkoxy optionally substituted by one or more fluorine atoms;R 3 represents a 5- or 6-membered heterocyclic ring, the ring being optionally substituted;R 4 represents a 4-, 5-, 6-, or 7-membered heterocyclic ring, the ring being optionally fused to a benzene ring or a 5- or 6-membered heterocyclic ring, the ring system as a whole being optionally substituted;X represents CH or N; andL is absent,or represents a cyclic group of formula Ia, STR2or represents a chain of formula Ib, STR3and pharmaceutically acceptable salts thereof, are useful in therapy, in particular in the treatment of benign prostatic hyperplasia.