210558-66-0 Usage
Description
(R,2S)-N-Pyrrolidinyl norephedrine HCL, a derivative of norephedrine, is a sympathomimetic agent that functions as a central nervous system stimulant and a vasoconstrictor. It is known for its effectiveness in alleviating symptoms of congestion and respiratory issues, and is typically administered as a hydrochloride salt to improve its stability and solubility. This chemical compound has been incorporated into pharmaceutical formulations for the treatment of conditions such as nasal congestion, asthma, and certain types of shock. However, it requires cautious use and medical supervision to prevent adverse effects like increased heart rate, elevated blood pressure, and potential dependence.
Uses
Used in Pharmaceutical Industry:
(R,2S)-N-Pyrrolidinyl norephedrine HCL is used as a nasal decongestant for the treatment of nasal congestion, providing relief by constricting blood vessels in the nasal passages and reducing swelling.
(R,2S)-N-Pyrrolidinyl norephedrine HCL is also used as a bronchodilator to alleviate respiratory issues, such as those experienced in asthma, by relaxing and widening the airways to improve airflow.
Additionally, it is utilized in the treatment of certain types of shock, where its vasoconstrictive properties help to stabilize blood pressure and improve blood flow to vital organs. However, due to the potential for misuse and overuse leading to adverse effects, it is crucial that this chemical is administered under the guidance of a healthcare professional.
Check Digit Verification of cas no
The CAS Registry Mumber 210558-66-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,1,0,5,5 and 8 respectively; the second part has 2 digits, 6 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 210558-66:
(8*2)+(7*1)+(6*0)+(5*5)+(4*5)+(3*8)+(2*6)+(1*6)=110
110 % 10 = 0
So 210558-66-0 is a valid CAS Registry Number.
210558-66-0Relevant articles and documents
Synthesis method of chiral compound
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Paragraph 0159-0160; 0164, (2020/01/25)
The invention belongs to the technical field of chemical synthesis, and relates to a synthetic method of a chiral compound, in particular to a synthetic method of (1R, 2S)-1-phenyl-2-(pyrrolidine-1-yl) propan-1-ol. According to an ingenious synthesis strategy, asymmetric reduction can be realized during carbonyl reduction, and a target compound can be directly obtained at high yield. The problem that a target compound cannot be obtained at high yield through asymmetric reduction in the prior art is solved. Moreover, the synthesis of a high-purity compound (A) can be realized by using cheap hydrochloric acid and zinc chloride; in addition, no isomer is wasted; and according to the method, the use of norephedrine controlled product is avoided; the raw materials are cheap and easy to obtain,so that the synthesis cost is reduced; moreover, the preparation method disclosed by the invention is easy for industrial large-scale production.
