210581-27-4Relevant academic research and scientific papers
Two-step N-acylindazole to N-alkylindazole reduction. Further synthetic studies on the serotonergic agonist AL-34662
Conrow, Raymond E.,Delgado, Pete,Dean, W. Dennis,Callen, Gary R.,Plummer, Scott V.
, p. 2348 - 2350 (2008/09/18)
A synthesis of the title compound, operable on kilogram scale, employs reductive acetylation of an N-acylindazole to give a hemiaminal acetate followed by deacetoxylation to the corresponding N-alkylindazole.
1-((S)-2-aminopropyl)-1H-indazol-6-ol: A potent peripherally acting 5-HT2 receptor agonist with ocular hypotensive activity
May, Jesse A.,Dantanarayana, Anura P.,Zinke, Paul W.,McLaughlin, Marsha A.,Sharif, Najam A.
, p. 318 - 328 (2007/10/03)
Serotonin 5-HT2 receptor agonists have been identified as a potential new class of agents for the treatment of ocular hypertension and glaucoma. The initially reported tryptamine analogues displayed either poor solution stability, potent centra
