210687-23-3

Upstream product

• 512-04-9 diosgenin 
• 210687-09-5 (25R)-3β-(benzyloxy)-5α-spirostan-6β-ol 
• 210687-05-1 3β-O-benzylchlorogenin 
• 210687-15-3 (3S,5S,6R,8R,9S,10R,13S,14S,17R)-3,6-Bis-benzyloxy-17-[(1R,5R)-6-(tert-butyl-dimethyl-silanyloxy)-1,5-dimethyl-hexyl]-10,13-dimethyl-hexadecahydro-cyclopenta[a]phenanthren-16-one 
• 210687-13-1 (3S,5S,6R,8R,9S,10R,13S,14S,16S,17R)-3,6-Bis-benzyloxy-17-[(1R,5R)-6-(tert-butyl-dimethyl-silanyloxy)-1,5-dimethyl-hexyl]-10,13-dimethyl-hexadecahydro-cyclopenta[a]phenanthren-16-ol 
• 210687-12-0 (3S,5S,6R,8R,9S,10R,13S,14S,16S,17R)-3,6-Bis-benzyloxy-17-((1R,5R)-6-hydroxy-1,5-dimethyl-hexyl)-10,13-dimethyl-hexadecahydro-cyclopenta[a]phenanthren-16-ol 
• 210687-07-3 3-O-benzyl laxogenin 
• 146333-24-6 3-O-benzyl diosgenin 
• 100-39-0 benzyl bromide 
• 210687-21-1 (3S,5S,6R,8R,9S,10R,13S,14S,15R,17R)-3,6-Bis-benzyloxy-15-hydroxy-17-((1R,5R)-6-hydroxy-1,5-dimethyl-hexyl)-10,13-dimethyl-hexadecahydro-cyclopenta[a]phenanthren-16-one 
• 210687-10-8 (25R)-3β,6β-bis(benzyloxy)-5α-spirostane 

Relevant academic research and scientific papers

Synthesis of (25R)-5α-Cholestane-3β,6β,15α,16β,26-pentol, a Cytostatic Starfish Steroid1

The synthesis of (25R)-5αa-cholestane-3β,6β 15α,16β,26-pentol (1a), a marine cytostatic steroid, has been achieved in 13 steps (7.8% overall yield) starting from commercially available diosgenin (2). A key step in the synthesis was the dimethyldioxirane oxidation of the enolsilane 16 to introduce the 15α-hydroxy group in the D ring.