210896-25-6Relevant academic research and scientific papers
A convenient catalytic method for the synthesis of ethers from alcohols and carbonyl compounds
Fujii, Yasuyuki,Furugaki, Hisakazu,Tamura, Eiko,Yano, Shinji,Kita, Katsumi
, p. 456 - 463 (2007/10/03)
Dialkyl ethers and alkyl fluoroalkyl ethers are obtained in excellent yields by the reaction of alcohols and carbonyl compounds in the presence of Pd/C under the atmospheric pressure of hydrogen, when water produced by the reaction is continuously removed by bubbling hydrogen through the reaction mixture.
A new fluorous/organic amphiphilic ether solvent, F-626: Execution of fluorous and high temperature classical reactions with convenient biphase workup to separate product from high boiling solvent
Matsubara, Hiroshi,Yasuda, Shinji,Sugiyama, Hiroyuki,Ryu, Ilhyong,Fujii, Yasuyuki,Kita, Katsumi
, p. 4071 - 4076 (2007/10/03)
A new fluorous/organic amphiphilic ether solvent, 1H,1H,2H,2H-perfluorooctyl 1,3-dimethylbutyl ether (F-626), is introduced. The basic properties of F-626, especially the partition coefficients with organic solvents/FC-72 (perfluorohexane), were investigated. F-626 was easy to remove by fluorous biphase treatment. Using F-626 as a solvent, LAH reduction, catalytic hydrogenation, and fluorous reductive radical reactions were successful. Classical high temperature reactions up to 200°C, such as the Vilsmeier formylation, the Wolff-Kishner reduction, and the Diels-Alder reaction, were also examined in F-626. The yields of the products in F-626 were almost comparable with those conducted in common organic solvents, which prove that F-626 has the potential to be an easily recyclable high boiling solvent.
