21095-64-7 Usage
Description
2-Phenyl-benzooxazole-5-carboxylic acid is a chemical compound with the molecular formula C15H11NO3. It is a benzooxazole derivative characterized by a phenyl group attached to the carbon at position 2 of the benzooxazole ring and a carboxylic acid group at position 5. 2-PHENYL-BENZOOXAZOLE-5-CARBOXYLIC ACID has garnered interest due to its potential applications in various fields, particularly in the pharmaceutical industry, where it has been studied for its anti-inflammatory and analgesic properties. Furthermore, it has been investigated for its potential use as a building block in organic synthesis and for its possible role in the development of new materials with optoelectronic properties.
Uses
Used in Pharmaceutical Industry:
2-Phenyl-benzooxazole-5-carboxylic acid is used as a pharmaceutical compound for its anti-inflammatory and analgesic properties, making it a candidate for the development of new drugs to treat pain and inflammation.
Used in Organic Synthesis:
In the field of organic synthesis, 2-Phenyl-benzooxazole-5-carboxylic acid is used as a building block, contributing to the creation of more complex organic molecules that can have various applications in different industries.
Used in Material Science:
2-Phenyl-benzooxazole-5-carboxylic acid is used in the development of new materials with optoelectronic properties, potentially contributing to advancements in areas such as electronics, photonics, and energy-efficient technologies.
Check Digit Verification of cas no
The CAS Registry Mumber 21095-64-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,1,0,9 and 5 respectively; the second part has 2 digits, 6 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 21095-64:
(7*2)+(6*1)+(5*0)+(4*9)+(3*5)+(2*6)+(1*4)=87
87 % 10 = 7
So 21095-64-7 is a valid CAS Registry Number.
21095-64-7Relevant articles and documents
p-Toluenesulfonic acid-catalyzed metal-free formal [4?+?1] heteroannulation via N[sbnd]H/O[sbnd]H/S[sbnd]H functionalization: One-pot access to 2-aryl/hetaryl/alkyl benzazole derivatives
Srivastava, Abhijeet,Shukla, Gaurav,Singh, Maya Shankar
, p. 879 - 887 (2017/01/25)
A concise and direct one-pot [4?+?1] synthetic strategy for the construction of 2-substituted benzazoles such as benzoxazoles and benzothiazoles has been disclosed in high yields (80–98%) by cascade coupling reaction of 2-amino(thio)phenols with β-oxodithioesters. The current approach enables N[sbnd]H/O[sbnd]H/S[sbnd]H functionalization in one-pot under solventless condition leading to diverse benzazoles without use of any external metal. A wide range of 2-amino(thio)phenols and β-oxodithioesters are compatible toward this transformation with excellent functional group tolerance. Furthermore, we preempt the wider implications of this novel strategy by demonstrating its compatibility toward versatile diversification of DNA Topoisomerase-II inhibitors.
Benzoxazoles as transthyretin amyloid fibril inhibitors: Synthesis, evaluation, and mechanism of action
Razavi, Hossein,Palaninathan, Satheesh K.,Powers, Evan T.,Wiseman, R. Luke,Purkey, Hans E.,Mohamedmohaideen, Nilofar N.,Deechongkit, Songpon,Chiang, Kyle P.,Dendle, Maria T. A.,Sacchettini, James C.,Kelly, Jeffery W.
, p. 2758 - 2761 (2007/10/03)
Benzoxazoles pevent misfolding: Benzoxazole-based inhibitors of transthyretin (TTR) amyloid fibril formation are among the most effective found to date. They stabilize TTR against both acid-mediated misfolding and urea denaturation by raising the activati
