211430-93-2Relevant articles and documents
A systematic study on the use of different organocatalytic activation modes for asymmetric conjugated addition reactions of isoindolinones
Scorzelli, Francesco,Di Mola, Antonia,De Piano, Francesco,Tedesco, Consiglia,Palombi, Laura,Filosa, Rosanna,Waser, Mario,Massa, Antonio
, p. 819 - 828 (2017/01/28)
In this article we describe a series of new asymmetric Michael reactions of carboxylate-3-substituted isoindolinones used as nucleophiles in the synthesis of valuable chiral tetrasubstituted derivatives. It has been shown that the reactivity and enantiose
Halolactonization of γ-acetylenic acids: systhesis of novel spiroisoindole halobutyrolactones
Rammah, Mohamed M.,Othman, Mohamed,Msaddek, Moncef,Rammah, Mohamed B.
scheme or table, p. 1971 - 1981 (2009/04/06)
γ-Acetylenic carboxylic acids are cyclized to spirohalo butyrolactones, in the presence of NBS or NIS and K2CO3. The corresponding 5(E)-haloalkylidene-spirobutyrolactones were isolated in high yields, and this process constitutes an easy and efficient route to analogous structures of natural products of biological interest.