211516-63-1 Usage
Uses
Used in Pharmaceutical Industry:
Benzo[3,4]-18-norandrosta-3,5-diene-3(2'H)-carboxylic acid, 3',4',5',6'-tetrahydro-4',4',9,14-tetraMethyl-17-oxo-, Methyl ester, (3β,4β,8α,9β,10α,13α,14β)(9CI) is used as a pharmaceutical intermediate for the development of drugs targeting various medical conditions. Its unique structure and potential biological activities make it a promising candidate for the synthesis of new therapeutic agents.
Used in Organic Chemistry Research:
In the field of organic chemistry, Benzo[3,4]-18-norandrosta-3,5-diene-3(2'H)-carboxylic acid, 3',4',5',6'-tetrahydro-4',4',9,14-tetraMethyl-17-oxo-, Methyl ester, (3β,4β,8α,9β,10α,13α,14β)- (9CI) serves as a valuable research tool for studying the synthesis and modification of steroidal compounds. Its complex structure and stereochemistry provide opportunities for exploring novel synthetic pathways and developing innovative methodologies for the preparation of related compounds.
Used in Drug Design and Development:
Benzo[3,4]-18-norandrosta-3,5-diene-3(2'H)-carboxylic acid, 3',4',5',6'-tetrahydro-4',4',9,14-tetraMethyl-17-oxo-, Methyl ester, (3β,4β,8α,9β,10α,13α,14β)(9CI)'s potential biological activities and structural features make it a candidate for drug design and development. It can be further modified and optimized to enhance its therapeutic properties, leading to the creation of new drugs with improved efficacy and selectivity.
Used in Steroid Hormone Analysis:
Due to its structural similarity to natural steroid hormones, Benzo[3,4]-18-norandrosta-3,5-diene-3(2'H)-carboxylic acid, 3',4',5',6'-tetrahydro-4',4',9,14-tetraMethyl-17-oxo-, Methyl ester, (3β,4β,8α,9β,10α,13α,14β)(9CI) can be employed as a reference compound in the analysis and identification of steroid hormones. This aids in understanding their roles in various physiological processes and the development of hormone-related therapies.
Check Digit Verification of cas no
The CAS Registry Mumber 211516-63-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,1,1,5,1 and 6 respectively; the second part has 2 digits, 6 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 211516-63:
(8*2)+(7*1)+(6*1)+(5*5)+(4*1)+(3*6)+(2*6)+(1*3)=91
91 % 10 = 1
So 211516-63-1 is a valid CAS Registry Number.
211516-63-1Relevant academic research and scientific papers
Epoxides, cyclic sulfites, and sulfate from natural pentacyclic triterpenoids: Theoretical calculations and chemical transformations
Garcia-Granados, Andres,Lopez, Pilar E.,Melguizo, Enrique,Moliz, Juan N.,Parra, Andres,Simeo, Yolanda,Dobado, Jose A.
, p. 4833 - 4844 (2007/10/03)
Several triterpenic derivatives, with the A-ring functionalized, were semisynthesized from oleanolic and maslinic acids. The reactivities of sulfites, sulfate, and epoxides in these triterpene compounds were investigated under different reaction conditions. Moreover, contracted A-ring triterpenes (five-membered rings) were obtained, by different treatments of the sulfate 7. From the epoxide 8, deoxygenated and halohydrin derivatives were semisynthesized with several nucleophiles. Ozonolysis and Beckmann reactions were used to yield 4-aza compounds, from five-membered ring olanediene triterpenes. The X-ray structure of sulfate 7 is given and compared with density functional theory geometries. Theoretical 13C and 1H chemical shifts (gauge-invariant atomic orbital method at the B3LYP/6-31G*//B3LYP/6-31G* level) and 3JH,H coupling constants were calculated for compounds 5-9 and 34-36, identifying the (R)- or (S)-sulfur and α- or β-epoxide configurations together with 4-aza or 3-aza structures.
