211616-58-9

Upstream product

• 218601-09-3 Benzoic acid (3R,4R,5S)-4-benzyloxy-5-benzyloxymethyl-tetrahydro-thiophen-3-yl ester 
• 210548-19-9 (3R,4R,5S)-4-Benzyloxy-5-benzyloxymethyl-tetrahydro-thiophen-3-ol 

Downstream Products

• 211616-60-3 1-((3R,4R,5S)-4-Benzyloxy-5-benzyloxymethyl-3-fluoro-tetrahydro-thiophen-2-yl)-5-methyl-1H-pyrimidine-2,4-dione 
• 211616-59-0 Acetic acid (3R,4R,5S)-4-benzyloxy-5-benzyloxymethyl-3-fluoro-tetrahydro-thiophen-2-yl ester 

Relevant academic research and scientific papers

Synthesis and antiviral activity of L-2'-deoxy-2'-up-fluoro-4'- thionucleosides

L-2'-Deoxy-2'-up-fluoro-4'-thionucleosides were efficiently synthesized from D-xylose via L-4-thioarabitol derivative as a key intermediate and evaluated for antiviral activities against HIV-1, HSV-1,2 and HBV.

Ring contraction and rearrangement of 4-thiofuranose derivatives observed during dast fluorination in the synthesis of L-2'-'up'-fluoro-4'- thiothymidine

Ring contraction and rearrangement of 4-thiofuranose derivatives were observed through the regioselective opening of the episulfonium ion formed during DAST fluorination in the synthesis of L-2'-'up'-fluoro-4'- thiothymidine.