211677-98-4

Upstream product

• 211677-97-3 4-methylphenyl 2-azido-3,4,6-tri-O-benzyl-2-deoxy-1-thio-β-D-galactopyranosside 
• 125760-22-7 p-methylphenyl 2-deoxy-2-azido-1-thio-β-D-galactopyranoside 
• 79781-69-4 2-azido-3,4,6-tri-O-benzyl-2-deoxy-D-galactopyranose 
• 98-88-4 benzoyl chloride 
• 117252-95-6 2-(trimethylsilyl)ethyl β-D-galactopyranoside 
• 67673-39-6 3,4,6-tri-O-acetyl-2-azido-2-deoxy-alpha-D-galactopyranosyl bromide 
• 79781-71-8 2-azido-3,4,6-tri-O-benzyl-2-deoxy-α-D-galactopyranosyl bromide 
• 128200-58-8 2-(trimethylsilyl)ethyl 2,3,6-tri-O-benzoyl-β-D-galactopyranoside 

Relevant academic research and scientific papers

Synthesis of some amino and carboxy analogs of galabiose; evaluation as inhibitors of the pilus protein PapG(J)96 from Escherichia coli

The 2'-amino-2'-deoxy, 6-amino-6-deoxy, and 6-carboxy analogs of the reference inhibitor 2(trimethylsilyl)ethyl (α-D-galactopyranosyl)-(1→4)- β-d-galactopyranoside were synthesized and evaluated as inhibitors of the binding of the Escherichia coli-derived pilus protein PapG(J96), using an ELISA assay. The inhibitory efficiencies (K(rel); relative to the reference inhibitor) were: 157, 13, and 8, respectively. The results support the previously proposed combining site model, where the protein carries a negatively charged amino acid residue near HO-2' and HO-6 of the galabioside.