211869-52-2Relevant academic research and scientific papers
Enantioselective synthesis of optically active homoallylamines by nucleophilic addition of chirally modified allylboranes to N-silylimines
Itsuno, Shinichi,Watanabe, Katsuhiro,Matsumoto, Takeshi,Kuroda, Shizuc,Yokoi, Ayako,El-Shehawy, Ashraf
, p. 2011 - 2016 (1999)
Enantioselectivity in the allylboration of W-silylimines with a variety of chirally modified allylboron reagents has been examined. Optically active N-sulfonylarhino alcohols (16,17 and 19) derived from D-camphor and norephedrine were found to be efficient chiral ligands for the allylboration reagent. These reagents smoothly reacted with Ar-silylimines to give the corresponding homoallylic amines in a high level of enantioselectivity up to 96% ee.
