21193-80-6

Basic information

• Product Name: bromotubercidin
• Synonyms: bromotubercidin;5-broMo-7-(beta-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyriMidin-4-aMine;5-broMo-7-pentofuranosyl-7h-pyrrolo[2,3-d]pyriMidin-4-aMine;4-Amino-5-bromo-7-beta-D-ribofuranosyl-7H-pyrrolo[2,3-d]pyrimidine;NSC 103802
• CAS NO: 21193-80-6
• Molecular Formula: C₁₁H₁₃BrN₄O₄
• Molecular Weight: 345.14932
• Mol File: 21193-80-6.mol
• Article Data: 7

Chemical Properties

• Melting Point: 232 °C(Solv: methanol (67-56-1))
• Boiling Point: 686.9°C at 760 mmHg
• Flash Point: 369.2°C
• Appearance: /
• Density: 2.26g/cm³
• Vapor Pressure: 8.16E-20mmHg at 25°C
• Refractive Index: 1.869
• PKA: 12.32±0.70(Predicted)
• CAS DataBase Reference: bromotubercidin(CAS DataBase Reference)
• NIST Chemistry Reference: bromotubercidin(21193-80-6)
• EPA Substance Registry System: bromotubercidin(21193-80-6)

Safety Data

• Hazardous Substances Data: 21193-80-6(Hazardous Substances Data)

Usage

Chemical Properties

White powder

InChI:InChI=1/C11H13BrN4O4/c12-4-1-16(10-6(4)9(13)14-3-15-10)11-8(19)7(18)5(2-17)20-11/h1,3,5,7-8,11,17-19H,2H2,(H2,13,14,15)/t5-,7-,8-,11-/m1/s1

Upstream product

• 60343-84-2 2',3',5'-tri-O-acetyltubercidin 
• 22276-95-5 5-bromo-4-chloro-7H-pyrrolo[2,3-d]pyrimidine 
• 952429-11-7 (2R,3R,4R,5R)-2-((benzoyloxy)methyl)-5-(5-bromo-4-chloro-7H-pyrrolo[2,3-d]pyrimidin-7-yl)tetrahydrofuran-3,4-diyl dibenzoate 

Downstream Products

• 69-33-0 tubercidin 
• 40725-89-1 4-amino-N7-(3'-deoxy-β-D-ribofuranosyl)pyrrolo[2,3-d]pyrimidine 
• 1428254-19-6 (2R,3R,4R,5R)-2-(4-amino-5-bromo-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-5-(chloromethyl)tetra-hydrofuran-3,4-diol 
• 1252857-93-4 4-amino-5-(4-methoxyphenyl)-7-(β-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine 
• 1252857-91-2 4-amino-5-phenyl-7-(β-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine 

Relevant articles and documents

A containing spiro group of the pyrrolo [2, 3 - d] pyrimidine compound and its preparation method

The present invention provides a formula (I) of the formula (II) is shown including volute group of the pyrrolo [2, 3 - d] pyrimidine compounds and their pharmaceutically acceptable salt, and method of preparation and application. Compounds of this class

SELECTIVE INHIBITORS OF PROTEIN ARGININE METHYL TRANSFERASE 5 (PRMT5)

The disclosure is directed to compounds of Formula I, Formula II, and Formula III [Formulas should be inserted here]. Methods of their use and preparation are also described.

Synthesis of 8-(1,2,3-triazol-1-yl)-7-deazapurine nucleosides by azide–alkyne click reactions and direct C[sbnd]H bond functionalization

Treatment of toyocamycin or sangivamycin with 1,3-dibromo-5,5-dimethylhydantoin in MeOH (rt/30?min) gave 8-bromotoyocamycin and 8-bromosangivamycin in good yields. Nucleophilic aromatic substitution of 8-bromotoyocamycin with sodium azide provided novel 8