212000-38-9Relevant academic research and scientific papers
Continuous multiple liquid-liquid separation: Diazotization of amino acids in flow
Hu, Dennis X.,O'Brien, Matthew,Ley, Steven V.
supporting information; experimental part, p. 4246 - 4249 (2012/10/08)
A second-generation laboratory-scale, modular liquid-liquid separation device based on computer-controlled high-pressure pumps and a high-resolution digital camera has been invented. The diazotization of amino acids to produce valuable chiral hydroxyacids is demonstrated in flow for the first time. The use of a triple-separator system in conjuction with the developed diazotization process allows the safe and efficient production and automated isolation of multigram quantities of valuable chiral hydroxyacids.
Optically pure and enriched isomers of chelating ligands and contrast agents
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Page/Page column sheet 4, (2008/06/13)
Organic chelating ligands, organic chelating ligand precursors, and metal chelates are disclosed. Methods for synthesizing the same are also described, including methods for preparing optically-enriched or optically-pure compositions of the same.
METHOD FOR THE PRODUCTION OF BICYCLIC AROMATIC AMINO ACIDS AND INTERMEDIATE PRODUCTS THEREOF
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Page/Page column 41, (2010/02/08)
Disclosed is a method for producing integrin inhibitors of formula (I), wherein R1, R2, R3, R4, R5, and X have the meanings indicated in claim 1, and intermediate compounds.
