21202-70-0

Basic information

• Product Name: 4-Quinolinol, 6-methoxy-2-(4-methoxyphenyl)-
• CAS NO: 21202-70-0
• Molecular Formula: C17H15NO3
• Molecular Weight: 281.311
• Mol File: 21202-70-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-Quinolinol, 6-methoxy-2-(4-methoxyphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Quinolinol, 6-methoxy-2-(4-methoxyphenyl)-(21202-70-0)
• EPA Substance Registry System: 4-Quinolinol, 6-methoxy-2-(4-methoxyphenyl)-(21202-70-0)

Safety Data

• Hazardous Substances Data: 21202-70-0(Hazardous Substances Data)

Upstream product

• 100-07-2 4-methoxy-benzoyl chloride 
• 104-94-9 4-methoxy-aniline 
• 37771-22-5 chlorure de methoxy-4 N-(methoxy-4 phenyl) benzimidoyle 
• 27865-44-7 4-methoxy-N-(4-methoxyphenyl)benzamide 
• 100-06-1 1-(4-methoxyphenyl)ethanone 
• 22027-50-5 methyl 3-(4-methoxybenzoyl)acetate 
• 2881-83-6 ethyl 4-methoxybenzoylacetate 

Downstream Products

• 801233-59-0 4-bromo-6-methoxy-2-(4-methoxyphenyl)quinoline 
• 21202-81-3 4-chloro-6-methoxy-2-(4-methoxyphenyl)quinoline 
• 801233-65-8 4-bromo-2-(4-hydroxyphenyl)quinolin-6-ol 
• 801233-68-1 4-chloro-2-(4-hydroxyphenyl)quinolin-6-ol 
• 801234-04-8 2-(4-hydroxyphenyl)-4-vinylquinolin-6-ol 
• 801233-89-6 4-cyano-6-methoxy-2-(4-methoxyphenyl)quinoline 
• 801234-33-3 4-acetyl-2-(4-hydroxyphenyl)quinolin-6-ol 
• 801234-13-9 2-(4-hydroxyphenyl)-4-[(trimethylsilyl)ethynyl]quinolin-6-ol 
• 801234-89-9 3-chloro-6-methoxy-2-(4-methoxyphenyl)quinolin-4-ol 

Relevant articles and documents

ERβ ligands. Part 4: Synthesis and structure-activity relationships of a series of 2-phenylquinoline derivatives

A new class of estrogen receptor β (ERβ) ligands based on the 2-phenylquinoline scaffold was prepared. Several analogues with C4 substitution displayed high affinity (3-5 nM) and significant selectivity (up to 83-fold) for ERβ. The best compound, 13b, was profiled as a selective partial agonist for ERβ at 1 μM in a cell-based transcriptional assay. Uterine weight bioassay of 13b indicated no activation of ERα in vivo.