37771-22-5

Upstream product

• 27865-44-7 4-methoxy-N-(4-methoxyphenyl)benzamide 
• 100-07-2 4-methoxy-benzoyl chloride 
• 104-94-9 4-methoxy-aniline 

Downstream Products

• 84425-51-4 2-(4-Methoxy-phenyl)-5,7-diphenyl-[1,3,4]thiadiazolo[3,2-a]pyridin-4-ylium; chloride 
• 104-94-9 4-methoxy-aniline 
• 82020-07-3 bis (methoxy-4 phenyl)-3,4 ethyl-5 4H-triazole-1,2,4 
• 21202-70-0 6-methoxy-2-(4-methoxy-phenyl)-quinolin-4-ol 
• 101971-78-2 Acetic acid 4-[3-(4-acetoxy-phenyl)-5-ethyl-[1,2,4]triazol-4-yl]-phenyl ester 
• 82020-39-1 4,4'-(3-ethyl-4H-1,2,4-triazol-4,5-diyl)-bis-phenol 

Relevant academic research and scientific papers

Domino 1,4- And 1,6-Addition Reactions of Ketene Silyl Acetals to Dialkynyl Imines Promoted by Aluminum Chloride: Synthesis of Multifunctionalized β-Lactams

Domino 1,4- and 1,6-addition reactions of ketene silyl acetals to dialkynyl imines are disclosed. Aluminum chloride promoted domino 1,4- and 1,6-addition reactions of ketene silyl acetals to dialkynyl imines to give a variety of alkenyl iminocyclobutenones in moderate to good yields. The chemoselective reduction of alkenyl iminocyclobutenones and the subsequent thermal rearrangement of resulting alkenyl aminocyclobutenones in the presence of appropriate amines provided cis or trans multifunctionalized β-lactams in moderate to high yields with good to high diastereoselectivities.

N-alkylation of α-iminophosphonates and application to Horner-Wadsworth-Emmons reaction

N-Alkylation of α-iminophosphonates with Grignard reagents gives α-N-alkylaminophosphonates. A subsequent Horner-Wadsworth-Emmons reaction of the intermediary α-metalated phosphonate takes place with aldehydes to give enamines. The enamine thus prepared reacts with MVK to give a four-component coupling product.

Umpolung of Michael acceptors catalyzed by N-heterocyclic carbenes

N-Heterocyclic carbenes can catalyze β-alkylations of a range of α,β-unsaturated esters, amides, and nitriles that bear pendant leaving groups to form a variety of ring sizes. In this process, the nucleophilic catalyst transiently transforms the normally electrophilic β carbon into a nucleophilic site through an unanticipated addition-tautomerization sequence. Copyright

4,5-bis(aryl) 4H-1,2,4-triazoles derivatives and analgesic use

A novel process for the preparation of 4H-1,2,4-triazoles in their racemic or optically active forms of the formula STR1 wherein the compounds have analgesic activity.

TETRAZOLES. XXVIII PREPARATION AND PROPERTIES OF 2,3-DIPHENYL-5-ALKYLTETRAZOLIUM SALTS

The oxidation of 1,5-diphenyl-3-alkylformazanes by potassium permanganate in methylene chloride (chloroform)-water two-phase systems is a convenient method for the preparation of 2,3-diphenyl-5-alkyltetrazolium salts.The 2,3-diphenyl-5-alkyltetrazolium salts can be used as catalysts for interphase transfer in reactions proceeding in organic solvent-water two-phase systems, with a neutral or acid aqueous phase.The catalytic activity of 2,3-diphenyl-5-alkyltetrazolium salts increases with increase in the length of the alkyl substituent in the 5-position of the tetrazole ring.

Synthesis and analgesic activity in 1,2,4-triazole series

Derivatives of 1,2,4-triazole have been synthesized. Several methods of synthesis were used and the analgetic and antiinflammatory properties of the products obtained were studied. Structural requirements for analgetic activity were specified. Certain compounds show a high degree of analgetic activity. One of them, RU 39813, has been chosen for extended pharmacological study.