212121-59-0Relevant academic research and scientific papers
Highly enantioselective synthesis of cyclic and functionalized α-amino acids by means of a chiral phase transfer catalyst
Corey,Noe, Mark C,Xu, Feng
, p. 5347 - 5350 (1998)
The chiral quaternary ammonium salt 1 serves as phase transfer catalyst for the enantioselective conversion of the glycine derivative 2 to a variety of cyclic and acyclic chiral α amino acids with enantioselectivities as high as 200:1 in alkylation and Michael addition reactions.
Phase transfer catalyzed asymmetric alkylations of imine glycinamides
Kumar, Sanjeev,Ramachandran, Uma
, p. 2539 - 2545 (2007/10/03)
Herein we report the use of achiral imine glycinamides as substrates for asymmetric alkylations using chiral phase-transfer catalysts for the first time. Initially tried for obtaining a key intermediate for the synthesis of levobupivacaine, we expanded th
