212127-71-4 Usage
Uses
Used in Organic Chemistry:
3-(Allyloxy)prop-1-en-2-ylboronic acid pinacol ester is used as a reagent for facilitating Suzuki-Miyaura cross-coupling reactions, which are crucial for the formation of carbon-carbon bonds in organic synthesis. Its reactivity and stability make it an essential component in the synthesis of various organic compounds.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 3-(Allyloxy)prop-1-en-2-ylboronic acid pinacol ester is used as a synthetic intermediate for the development of new drugs. Its ability to form carbon-carbon bonds through cross-coupling reactions allows for the creation of complex molecular structures that can be used as potential therapeutic agents.
Used in Material Science:
3-(Allyloxy)prop-1-en-2-ylboronic acid pinacol ester is utilized as a building block in the synthesis of advanced materials, such as polymers and composites. Its reactivity and compatibility with various monomers enable the development of materials with tailored properties for specific applications, including electronics, coatings, and adhesives.
Used in Research and Development:
In academic and industrial research settings, 3-(Allyloxy)prop-1-en-2-ylboronic acid pinacol ester is employed as a key component in the exploration of new chemical reactions and synthetic pathways. Its unique reactivity and stability make it an attractive candidate for studying reaction mechanisms and developing novel synthetic strategies.
Check Digit Verification of cas no
The CAS Registry Mumber 212127-71-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,1,2,1,2 and 7 respectively; the second part has 2 digits, 7 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 212127-71:
(8*2)+(7*1)+(6*2)+(5*1)+(4*2)+(3*7)+(2*7)+(1*1)=84
84 % 10 = 4
So 212127-71-4 is a valid CAS Registry Number.
212127-71-4Relevant academic research and scientific papers
Multigram Synthesis of Heterabicyclo[n.1.0]alkan-1-yl Trifluoroborates
Kleban, Ihor,Krokhmaliuk, Yevhen,Reut, Sofiia,Shuvakin, Serhii,Pendyukh, Vyacheslav V.,Khyzhan, Oleksandr I.,Yarmoliuk, Dmytro S.,Tymtsunik, Andriy V.,Rassukana, Yuliya V.,Grygorenko, Oleksandr O.
, p. 6551 - 6560 (2020/09/17)
An approach to the synthesis of oxa- and azabicyclo[n.1.0]alkan-1-yl trifluoroborates on a multigram scale was developed. Two synthetic strategies were evaluated: the first based on the lithiation–borylation of the corresponding 2-bromoallyl derivatives, and the other relying on regioselective hydroboration of the appropriate hetera-substituted enynes. The second method appeared to be more efficient in terms of scalability and substrate scope. Further steps included ring closing-metathesis, mild palladium-catalyzed cyclopropanation with diazomethane, and reaction with KHF2 and furnished the title compounds in up to 50 g scale in a single run (10–41 % overall yield, 4–5 steps).
TYROSINE KINASE INHIBITORS
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Page/Page column 170-171, (2011/08/03)
The present invention relates to pyridazin-4(1H)-one derivatives, that are useful for treating cellular proliferative diseases, for treating disorders associated with MET activity, and for inhibiting the receptor tyrosine kinase MET. The invention also related to compositions which comprise these compounds, and methods of using them to treat cancer in mammals.
