212199-04-7

Upstream product

• 212199-00-3 Chloro-acetic acid (2R,3R,4R,5S,6S)-3-acetoxy-5-benzyloxy-2-(3-benzyloxycarbonylamino-propoxy)-6-methyl-tetrahydro-pyran-4-yl ester 
• 212199-02-5 3-N-benzyloxycarbonylaminopropyl (3-O-allyl-2,4-6-tri-O-benzyl-α-D-glucopyranosyl)-(1-3)-2-O-acetyl-4-O-benzyl-α-L-rhamnopyranoside 
• 132799-05-4 3-N-benzyloxycarbonylaminopropyl 2,3-di-O-acetyl-4-O-benzyl-α-L-rhamnopyranoside 
• 212199-01-4 Acetic acid (2R,3R,4R,5R,6S)-5-benzyloxy-2-(3-benzyloxycarbonylamino-propoxy)-4-hydroxy-6-methyl-tetrahydro-pyran-3-yl ester 
• 132799-06-5 [3-((2R,3R,4S,5R,6S)-5-Benzyloxy-3,4-dihydroxy-6-methyl-tetrahydro-pyran-2-yloxy)-propyl]-carbamic acid benzyl ester 
• 34637-22-4 3-[(N-benzyloxycarbonyl)amino]propanol 
• 128716-35-8 3,4,6-tri-O-acetyl-2-O-allyl-α,β-D-galactopyranosyl trichloroacetimidate 
• 212199-03-6 3-N-benzyloxycarbonylaminopropyl (2,4,6-tri-O-benzyl-α-D-glucopyranosyl)-(1-3)-2-O-acetyl-4-O-benzyl-α-L-rhamnopyranoside 

Downstream Products

• 212199-05-8 C₆₅H₇₇NO₂₁ 

Relevant academic research and scientific papers

Synthesis of four spacer-containing 'tetrasaccharides' that represent four possible repeating units of the capsular polysaccharide of Streptococcus pneumoniae type 6B

In the framework of studies towards oligosaccharide-conjugate based vaccines against Streptococcus pneumoniae, the synthesis is reported of four spacer-containing 'tetrasaccharides' that each can be conceived as representing a repeating unit of the capsular polysaccharide of S. pneumoniae serotype 6B, namely, 3-aminopropyl D-ribityl-(5 → hydrogen phosphate → 2)- α-D-galactopyranosyl-(1 → 3)-α-D-glucopyranosyl-(1 → 3)-α-L- rhamnopyranoside, 3-aminopropyl α-L-rhamnopyranosyl-(1 → 4)-D-ribityl-(5 → hydrogen phosphate → 2)-α-D-galactopyranosyl-(1 → 3)-α-D-glucopyranoside, 3-aminopropyl α-D-glucopyranosyl-(1 → 3)-α-L-rhamnopyranosyl-(1 → 4)-D- ribityl-(5 → hydrogen phosphate → 2)-α-D-galactopyranoside, and α-D- galactopyranosyl-(1 → 3)-α-D-glucopyranosyl-(1 → 3)-α-L-rhamnopyranosyl- (1 → 4)-5-O-(3-aminopropyl hydrogen phosphate)-D-ribitol. Phosphorylations were carried out using the H-phosphonate method.