2122-68-1

Usage

Uses

Used in Agricultural Applications:
1H-Indole-3-acetic acid propyl ester is used as a plant growth regulator for promoting plant growth and development. It is involved in processes such as cell division, elongation, and differentiation, which are crucial for the overall health and productivity of plants.
Used in Plant Physiology Research:
1H-Indole-3-acetic acid propyl ester is used as a research tool for studying the mechanisms of plant growth and development, particularly in the context of auxin signaling pathways. Its role in phototropism, the process by which plants grow towards light, makes it a valuable compound for understanding how plants respond to environmental stimuli.
Used in Plant Biotechnology:
1H-Indole-3-acetic acid propyl ester is used as a component in plant tissue culture and genetic engineering applications. Its ability to influence plant growth and development makes it a potential candidate for improving crop yields and stress resistance in genetically modified plants.
Used in Pharmaceutical Applications:
Although less well studied, 1H-Indole-3-acetic acid propyl ester may have potential applications in the pharmaceutical industry, particularly in the development of new drugs that target plant hormone receptors or pathways involved in human health and disease. Further research is needed to explore these possibilities.

Upstream product

• 87-51-4 indole-3-acetic acid 
• 764-02-3 1-diazopropane 
• 71-23-8 propan-1-ol 

Downstream Products

• 4802-79-3 1,2,3,4,6,7,12,12b-octahydroindolo(2,3-a)quinolizine 

Relevant academic research and scientific papers

Studies on difficult intramolecular hydroaminations in the context of four syntheses of alkaloid natural products

Examples of intramolecular alkene hydroaminations forming six-membered ring systems are rare, especially for systems in which the double bond is disubstituted. Such cyclizations have important synthetic relevance. Herein we report a systematic study of these cyclizations using recently developed Cope-type hydroamination methodologies. Difficult intramolecular alkene hydroaminations were used as key steps in syntheses of 2-epi-pumiliotoxin C, coniine, N-norreticuline and desbromoarborescidine A. This effort required the development of optimized hydroamination conditions to improve the efficiency of the cyclizations. Collectively, our results show that Cope-type cyclizations can be achieved on a variety of challenging substrates and proceed under similar conditions for both N-H and N-substituted hydroxylamines.

Stereochemistry of dimerisation of indole-3-acetic acid and its propyl ester

The mechanism, stereochemistry and products of the dimerisation of indole-3-acetic acid 1a and its propyl ester 1b in TFA and H3PO4 have been investigated. The major products in both acids were 2-(indolin-2-yl)indole dimers, 3a/b, which were readily converted into the corresponding pentacyclic lactams 5a/b with the pyrido[1,2-a:3,4-b′]biindole skeleton. Ccompound 5a was studied by X-ray crystallography and shown to be the 2,3-trans-isomer. The reaction proceeds via electrophilic attack of the protonated species 2 on free 1 with steric approach control to form the trans-stereoisomeric 3 and/or 5. Acta Chemica Scandinavica 1998.