21224-34-0

Upstream product

• 583-39-1 2,3-dihydrobenzimidazol-2-thione 
• 106-93-4 ethylene dibromide 
• 134469-07-1 Benzimidazol-2-thiol 
• 1009-70-7 (4,5-dihydro-thiazol-2-yl)-phenyl-amine 
• 420-12-2 thirane 
• 4857-06-1 2-chloro-1H-benzoimidazole 
• 64648-13-1 S-ethenyl-S-(4-methylphenyl)-N-tosylsulfilimine 
• 107-06-2 1,2-dichloro-ethane 
• 22297-98-9 2-(2-chloro-ethylsulfanyl)-1H-benzoimidazole 

Downstream Products

• 2360-29-4 2-(phenylsulfanyl)-1H-benzimidazole 

Relevant academic research and scientific papers

Synthesis of benzimidazole-fused heterocycles by intramolecular oxidative C-N bond formation using hypervalent iodine reagents

A straightforward approach by dehydrogenative C-N coupling between aryl C-H and N-H bonds using a hypervalent iodine reagent under mild conditions offers a versatile and convenient method for synthesizing various benzimidazole-fused heterocycles. Georg Th

Catalyst-free, rapid synthesis of fused bicyclic thiazolo-pyrimidine and pyrimido-thiazine derivatives by a microwave-assisted method

The present investigation deals with the rapid microwave-assisted synthesis of compounds containing fused bicyclic systems. Dihydropyrimidines obtained via a microwave-assisted Biginelli reaction were treated with dibromo alkanes under microwave condition

RESEARCH IN THE FIELD OF UNSATURATED DERIVATIVES OF AZOLES. 12. REACTION OF BENZIMIDAZOLE-2-THIONE WITH 1,2-DIBROMOETHANE; TEMPLATE SYNTHESIS OF CORONANDS

Benzimidazole-2-thione and 2-(mercaptomethyl)benzimidazole react with 1,2-dibromoethane in the presence of caustic under conditions of interfacial catalysis, forming macrocyclic compounds along with linear compounds.

Synthesis and Spectral Studies of 2-Mercaptobenzimidazole Derivatives. II.

This communication describes synthesis and spectral data of new 2-mercaptobenzimidazole derivatives.

Synthese d'heterocycles en Catalyse par Transfert de Phase

A general study of the chemical behavior of heterocyclic anions, dianions and dianionic reagents under phase transfer catalysis conditions allowed us to synthesize various heterocyclic compounds such as imidazothiazole and derivatives; imidazothiazine and imidazobenzothiazepine.Reaction conditions e.g., catalyst, solvent, temperature, etc., are indicated.

Tricyclic imidazole derivatives

New tricyclic fused imidazole derivatives of the general formula (I), SPC1 wherein R1 stands for hydrogen or hydroxy, n is equal to zero or one, m is equal to zero, one or two, A stands for a group of the general formula (II), EQU1 wherein R2 represents hydrogen or hydroxy, R3 represents hydrogen or amino, or Q and Z each stand for nitrogen or a =C-- group, or A stands for a group of the general formula (III), EQU2 wherein R4 and R5 each represent hydrogen, methyl, chlorine or nitro, Were prepared by reacting a compound of the general formula (IV) SPC2 wherein A and n each have the same meanings as defined above, with a compound of the general formula (V), EQU3 wherein X stands for halogen, R6 stands for hydrogen and R7 stands for a group of the general formula (VI), in which m and X each have the same meanings as defined above, or R6 and R7 together stand for oxygen. The reaction is carried out optionally in the presence of a base. The compounds of the general formula (I) can be converted into their acid addition salts. The compounds of the general formula (I) as well as their acid addition salts exert antipyretic and antiphlogistic activities, inhibit the reproduction of viruses, and exert a protecting effect against albumine shock.