212315-75-8Relevant academic research and scientific papers
Stereoselective synthesis of Z-vinylsilanes via palladium-catalyzed direct intermolecular silylation of C(sp2)-H bonds
Pan, Jin-Long,Chen, Chao,Ma, Zhi-Gang,Zhou, Jia,Wang, Li-Ren,Zhang, Shu-Yu
, p. 5216 - 5219 (2017/11/06)
An efficient and convenient palladium-catalyzed direct intermolecular silylation of C(sp2)-H bonds by using disilanes as the silicon source with the assistance of a readily removable bidentate directing group is reported. This strategy provided a regio- and stereoselective protocol for exclusive synthesis of Z-vinylsilanes with reasonable to excellent yields and good functional group compatibility. Silylation of the isolated palladacycle intermediate revealed the Z-stereoselective pathway. Moreover, the practicality and effectiveness of this method were illustrated by a gram-scale experiment and further functionalization of the silylation product.
Synthesis of isocoumarins and α-pyrones via palladium-catalyzed annulation of internal alkynes
Larock, Richard C.,Doty, Mark J.,Han, Xiaojun
, p. 8770 - 8779 (2007/10/03)
A number of 3,4-disubstituted isocoumarins and polysubstituted α- pyrones have been prepared in good yields by treating halogen- or triflate- containing aromatic and α,β-unsaturated esters, respectively, with internal alkynes in the presence of a palladiu
