212499-87-1Relevant articles and documents
Synthesis and testing of new modified nucleosides
Jung, Michael E.,Nichols, Christopher J.,Kretschik, Oliver,Xu, Yue
, p. 541 - 546 (1999)
New efficient routes for the high-yielding synthesis of several classes of modified nucleosides have been developed. We have prepared both the D- and L-enantiomers of the methylene-expanded oxetanocin isonucleosides 1a-c and the L-2',3'-dideoxy isonucleosides 2abc (both the oxa and thia analogues) as well as new routes for the preparation of L-ribose and 2-deoxy L-ribose 3ab and their modified nucleosides 4.
