
Nucleosides and Nucleotides p. 541 - 546 (1999)
Update date:2022-08-04
Topics:
Jung, Michael E.
Nichols, Christopher J.
Kretschik, Oliver
Xu, Yue
New efficient routes for the high-yielding synthesis of several classes of modified nucleosides have been developed. We have prepared both the D- and L-enantiomers of the methylene-expanded oxetanocin isonucleosides 1a-c and the L-2',3'-dideoxy isonucleosides 2abc (both the oxa and thia analogues) as well as new routes for the preparation of L-ribose and 2-deoxy L-ribose 3ab and their modified nucleosides 4.
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