21262-87-3

Basic information

• Product Name: Isoxazole, 3-(4-bromophenyl)-5-methyl-
• CAS NO: 21262-87-3
• Molecular Formula: C10H8BrNO
• Molecular Weight: 238.084
• Mol File: 21262-87-3.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: Isoxazole, 3-(4-bromophenyl)-5-methyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Isoxazole, 3-(4-bromophenyl)-5-methyl-(21262-87-3)
• EPA Substance Registry System: Isoxazole, 3-(4-bromophenyl)-5-methyl-(21262-87-3)

Safety Data

• Hazardous Substances Data: 21262-87-3(Hazardous Substances Data)

Upstream product

• 108-22-5 Isopropenyl acetate 
• 29203-58-5 4-bromo-N-hydroxybenzenecarboximidoyl chloride 
• 29203-58-5 (Z)-4-bromo-N-hydroxybenzene-1-carbonimidoyl chloride 
• 25062-46-8 4-bromobenzaldehyde Oxime 
• 20511-04-0 (E)-4-(4-bromophenyl)but-3-ene-2-one 
• 106650-98-0 1-(4-bromophenyl)but-3-en-1-ol 
• 1122-91-4 4-bromo-benzaldehyde 
• 184165-64-8 1-(4-bromophenyl)-3-buten-1-one 
• 3815-31-4 4-(4-bromophenyl)but-3-en-2-one 
• 57342-22-0 2-bromo-1-(4-bromophenyl)ethanone oxime 
• 21293-19-6 [3-(4-bromo-phenyl)-5-methyl-4,5-dihydro-isoxazol-5-yl]-phenyl-methanone (E)-oxime 
• 21293-19-6 [3-(4-bromo-phenyl)-5-methyl-4,5-dihydro-isoxazol-5-yl]-phenyl-methanone (Z)-oxime 
• 21262-83-9 [3-(4-bromo-phenyl)-5-methyl-4,5-dihydro-isoxazol-5-yl]-phenyl-methanone 

Relevant articles and documents

CARDIAC SARCOMERE INHIBITORS

Provided are compounds of Formula (I): or a pharmaceutically acceptable salt thereof, wherein R1, R2, Y1, Y2, L1, and G1 are as defined herein. Also provided is a pharmaceutically acceptable composition comprising a compound of Formula (I), or a pharmaceutically acceptable salt thereof. Also provided are methods of using a compound of Formula (I), or a pharmaceutically acceptable salt thereof.

Thienopyrimidine derivative, preparation method thereof and application thereof in medicines

The invention provides a thienopyrimidine derivative, a preparation method thereof and an application thereof in medicines. Specifically, the invention relates to a compound represented by a formula I, wherein the radicals are defined in the description. The compound is effective tyrosine kinase inhibitors in one category, and is particularly suitable for being used as an EGFR and/or HER2 inhibitor.

Efficient and regioselective one-pot synthesis of 3-substituted and 3,5-disubstituted isoxazoles

(Figure Presented) A series of 3-substituted and 3,5-disubstituted isoxazoles have been efficiently synthesized in moderate to excellent yields by the reaction of N-hydroxyl-4-toluenesulfonamide with α,β-unsaturated aldehydes/ketones. This novel strategy is associated with readily available starting materials, mild conditions, high regioselectivity, and wide scope.