212953-29-2

Basic information

• Product Name: 2'-O-triethylsilylpaclitaxel-6-α-nitrate
• Synonyms: 2'-O-triethylsilylpaclitaxel-6-α-nitrate
• CAS NO: 212953-29-2
• Molecular Weight: 1029.18
• Mol File: 212953-29-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2'-O-triethylsilylpaclitaxel-6-α-nitrate(CAS DataBase Reference)
• NIST Chemistry Reference: 2'-O-triethylsilylpaclitaxel-6-α-nitrate(212953-29-2)
• EPA Substance Registry System: 2'-O-triethylsilylpaclitaxel-6-α-nitrate(212953-29-2)

Safety Data

• Hazardous Substances Data: 212953-29-2(Hazardous Substances Data)

Upstream product

• 212953-25-8 6-β-hydroxy-2'-O-triethylsilylpaclitaxel 
• 288153-44-6 6-oxo-2'-O-triethylsilylpaclitaxel 
• 212953-24-7 6-oxo-2'-O-triethylsilyl-7-α-paclitaxel 
• 200568-20-3 6-α-hydroxy-2'-O-triethylsilyl-7-α-paclitaxel 
• 212953-26-9 2'-O-triethylsilylpaclitaxel-6,7-β-cyclic sulfate 

Downstream Products

• 153212-75-0 [3H]-6alpha-Hydroxypaclitaxel 

Relevant articles and documents

Stereospecific synthesis of the major human metabolite of paclitaxel

The stereospecific synthesis of 6-α-hydroxy paclitaxel 10, the major human metabolite of paclitaxel, is described. The 6,7-α-diol 4, obtained from paclitaxel, is converted to the 6,7-β-cyclic sulfate followed by nitrate addition and reduction to afford the title compound. (C) 2000 Elsevier Science Ltd.