21300-07-2

Basic information

• Product Name: 5-methoxyfuran-2-carbaldehyde
• Synonyms: 2-furancarboxaldehyde, 5-methoxy-; 5-Methoxyfuraldehyde
• CAS NO: 21300-07-2
• Molecular Formula: C₆H₆O₃
• Molecular Weight: 126.11
• Mol File: 21300-07-2.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 221°C at 760 mmHg
• Flash Point: 87.5°C
• Density: 1.168g/cm³
• Vapor Pressure: 0.11mmHg at 25°C
• Refractive Index: 1.504
• CAS DataBase Reference: 5-methoxyfuran-2-carbaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 5-methoxyfuran-2-carbaldehyde(21300-07-2)
• EPA Substance Registry System: 5-methoxyfuran-2-carbaldehyde(21300-07-2)

Safety Data

• Hazardous Substances Data: 21300-07-2(Hazardous Substances Data)

Upstream product

• 87091-05-2 2-hydroxymethyl-5-methoxy furan 
• 25414-22-6 2-methoxyfuran 
• 68-12-2 N,N-dimethyl-formamide 
• 53869-94-6 Methyl 5-methoxy-2-furancarboxylate 
• 2527-99-3 methyl 5-bromo-2-furoate 
• 37112-31-5 levoglucosenone 
• 67-63-0 isopropyl alcohol 
• 1899-24-7 5-bromo-2-furancarboxaldehyde 
• 67-56-1 methanol 

Downstream Products

• 87091-19-8 2-(2-(5-methoxy)furanyl)-3-phenyl-1-pivaloylindoline 
• 214468-16-3 Benzoic acid (E)-3-(5-methoxy-furan-2-yl)-allyl ester 
• 130518-24-0 melodienone 
• 130518-23-9 isomelodienone 
• 87091-14-3 1-(2-(5-methoxy)furanyl)-2-phenyl-2-(2-pivaloylamododiphenyl)ethanol 

Relevant articles and documents

SYNTHESIS, KINETICS OF THE FORMATION, AND PHYSICAL PROPERTIES OF 5-ALKOXYFURFURALS

The reaction of 5-bromofurfural with potassium alkoxides in an alcohol medium was studied, and 5-alkoxyfurfurals and the products of their condensation with m-nitroacetophenone were obtained.A mechanism for the alkoxylation is proposed on the basis of the kinetic data.

Short and efficient synthesis of the antitumor heptenes melodienone and isomelodienone

The antitumor heptenes melodienone and isomelodienone were synthesized in 5 steps from 2-methoxyfuran (overall yield = 36 and 45% respectively) via oxidative ring-opening of a common methoxyfuran precursor.

Synhetic approaches to haplphytine. 2. Synthesis of 4-methylamino-1-(2-furanyl)-2-phenyl-2-(2-pivaloylamidophenyl)butan-1-one

Approaches to the synthesis of compounds related to the 7-aryl-7-(3-(1-hydroxy-2-aminophenyl))-9-methylamino-5,6-dioxononanoic acid moiety (3) of the alkaloid haplophytine and its dihydrobromide are described.Treatment of the dianion of phenyl (o-pivaloyl