213009-71-3

Upstream product

• 69739-34-0 t-butyldimethylsiyl triflate 
• 149401-42-3 (E)-5-(benzyloxy)pent-3-en-2-one 
• 100-39-0 benzyl bromide 
• 60656-87-3 benzyloxyacetoaldehyde 
• 622-08-2 2-Benzyloxyethanol 

Downstream Products

• 380356-02-5 2-{5-[2-(2-{3,4-bis-(tert-butyl-dimethyl-silanyloxy)-6-[2-(tert-butyl-diphenyl-silanyloxy)-ethyl]-tetrahydro-pyran-2-yl}-vinyl)-3-methyl-cyclopropyl]-1,3-dimethyl-penta-1,4-dienyl}-6-ethyl-5-methyl-3,6-dihydro-2H-pyran 
• 380355-87-3 {3,4-bis-(tert-butyl-dimethyl-silanyloxy)-6-[2-(tert-butyl-diphenyl-silanyloxy)-ethyl]-tetrahydro-pyran-2-yl}-methanol 
• 380355-85-1 3,4-bis-(tert-butyl-dimethyl-silanyloxy)-6-[2-(tert-butyl-diphenyl-silanyloxy)-ethyl]-tetrahydro-pyran-2-carbaldehyde 
• 1026880-67-0 6-benzyloxymethyl-4-(tert-butyl-dimethyl-silanyloxy)-2-[2-(tert-butyl-diphenyl-silanyloxy)-ethyl]-3,6-dihydro-2H-pyran 

Relevant academic research and scientific papers

Asymmetric hetero-Diels-Alder reaction of 1-alkyl-3-silyloxy-1,3-dienes with ethyl glyoxylate catalyzed by a chiral (salen)cobalt(II) complex

The hetero-Diels-Alder reactions of 1-alkyl-3-(tert- butyldimethylsilyl)oxy-1,3-butadienes with ethyl glyoxylate catalyzed by chiral salen-metal complexes have been studied. With a cobalt(II) complex as the catalyst, the reaction of 1-(2-benzyloxyethyl)-3-(tert- butyldimethylsilyl)oxy-1,3-butadiene with ethyl glyoxylate gave the Diels- Alder product in 75% isolated yield with the endo:exo ratio >99:1 and the enantiomeric excess ≤52%. The effects of temperature, catalyst and solvent are also discussed.