2131-02-4Relevant academic research and scientific papers
Convenient and regioselective synthesis of nucleoside phosphoramidate monoesters
Zhu, Jigang,Fu, Hua,Jiang, Yuyang,Zhao, Yufen
, p. 1927 - 1929 (2007/10/03)
We have developed a convenient and efficient method for the synthesis of nucleoside phosphoramidate monoesters. This step-wise synthesis, consisting of an ester exchange, reaction of the 5′-OH of nucleosides with fluorenylmethyl aryl phosphite, and an Ath
Reaction of ADP with amino acid methyl esters mediated by trimethylsilyl chloride.
Fu, Hua,Han,Zhao, Yu-Fen
, p. 134 - 135 (2007/10/03)
Reaction of ADP with amino acid methyl esters mediated by trimethylsilyl chloride in pyridine produced adenosine 5'-phosphoramidates in good yields under mild conditions, it is interesting that nucleophilic attack of amino acid methyl esters only occurred
