21339-47-9

Usage

Uses

Used in Polymer Industry:
3,3-Diethoxypropane-1,1-dicarboxylic acid diethyl ester is used as a crosslinking agent for the production of thermosetting resins. Its ability to efficiently crosslink with other compounds contributes to the creation of polymers with enhanced properties, such as improved durability and thermal stability.
Used in Adhesives Industry:
In the adhesives industry, 3,3-Diethoxypropane-1,1-dicarboxylic acid diethyl ester is used as a crosslinking agent to improve the bonding strength and stability of adhesive formulations. Its reactivity with other compounds allows for the development of adhesives with better performance characteristics.
Used in Coatings Industry:
3,3-Diethoxypropane-1,1-dicarboxylic acid diethyl ester is employed as a crosslinking agent in the formulation of coatings, enhancing their durability, resistance to wear, and overall performance. Its ability to crosslink with other compounds results in coatings with improved mechanical properties and resistance to environmental factors.
Used in Pharmaceutical Industry:
As a building block for the synthesis of various pharmaceuticals, 3,3-Diethoxypropane-1,1-dicarboxylic acid diethyl ester is used in the development of new drugs and therapeutic agents. Its unique structure and reactivity make it a valuable component in the creation of innovative pharmaceutical compounds.
Used in Agrochemical Industry:
3,3-Diethoxypropane-1,1-dicarboxylic acid diethyl ester is utilized as a building block in the synthesis of agrochemicals, such as pesticides and herbicides. Its versatility and reactivity contribute to the development of effective and environmentally friendly agrochemical products.

InChI:InChI=1/C13H24O6/c1-5-16-11(17-6-2)9-10(12(14)18-7-3)13(15)19-8-4/h10-11H,5-9H2,1-4H3

Upstream product

• 1634-04-4 tert-butyl methyl ether 
• 2032-35-1 Bromoacetaldehyde diethyl acetal 
• 105-53-3 diethyl malonate 
• 996-82-7 sodium diethylmalonate 

Downstream Products

• 1254985-01-7 2-(2,2-diethoxyethyl)-2-(5-phenylpent-4-ynyl)malonic acid diethyl ester 

Relevant academic research and scientific papers

Samarium Diiodide Catalyzed Radical Cascade Cyclizations that Construct Quaternary Stereocenters

SmI 2 -catalyzed radical cascade cyclizations were used to generate complex carbocyclic products bearing quaternary stereocenters with high selectivity. Bicyclic scaffolds containing four contiguous stereocenters and one quaternary stereocenter

Synthesis of derivatives of 1,2,6-trisubstituted-4-piperidones

Robinson-Schopf cyclisation was used to prepare several 1,2,6-trisubstituted-4-piperidones: 1,2,6-trimethyl-4-piperidone, tricyclic ketones 2 and 3 derivatives of coccinelline. In the case of 1,2,6-trimethyl-4-piperidone, a mixture of the trans and cis compounds 4 and 1 was obtained. The pure cis compound was prepared by another route.

Four nucleophilic additions to alkenynedioic acid derivatives in tandem; Efficient one-pot synthesis of bicyclo[4.2.0]octenols

When alkenynedioic acid derivatives were treated with a Grignard reagent, tandem cyclization and the incorporation of two molecules of the Grignard reagent occurred to give stereodefined bicyclo[4.2.0]octenols via four nucleophilic additions.

Synthesis of acyclic nucleoside derivatives

Methods and novel intermediates of the formula: wherein R6 and R7 are lower alkyl or benzyl or R6 and R7 taken together are —CH2CH2—, —CH2CH2CH2— or —CH2CH2CH2CH2CH2—, R8 is C1-C21 alkyl or a C2-C21 monounsaturated alkenyl, which may optionally be substituted with substitution substituents independently selected from the group consisting of hydroxy, C1-C6 alkyl, C1-C6 alkoxy, C1-C6 alkoxy C1-C6 alkyl, C1-C6 alkanoyl, amino, halo, cyano, azido, oxo, mercapto and nitro, and R9 is an alcohol protecting group. The intermediates are useful for the preparation of acyclic nucleoside derivatives of the formula: where one of R1 and R2 is an amino acid acyl group and the other of R1 and R2 is a —C(O)C3-C21 saturated or monounsaturated, optionally substituted alkyl and R3 is OH or H; or a pharmaceutically acceptable salt thereof.

Regioselective alkylation of guanines using 2-acetoxytetrahydrofurans

Reaction of silylated guanine derivatives with 2-acetoxy-4-benzoyloxymethyltetrahydrofuran in DMF or NMP resulted in selective N-9 alkylation. This was used as the basis for a regioselective synthesis of the anti-viral agents famciclovir and penciclovir.

Asymmetric Pauson-Khand cyclizations of 1-sulfinylenynes

The use of sulfoxides as chiral auxiliaries in intramolecular Pauson-Khand (PK) reactions is described. In particular, the tert-butylsulfinyl group acts as a very efficient chiral auxiliary in intramolecular PK reactions of 1-sulfinyl- 1,6-enynes. As the

Synthesis of 1-p-tolysulfinyl-1,3-dienes by intramolecular heck reactions

The first examples of the synthesis of 1,3-dienyl sulfoxides by Heck reactions are described. Both racemic and enantiomerically pure exocyclic 1- p-tolylsulfinyl-1,3-dienes 1 are readily prepared by the intramolecular Heck reaction of their corresponding vinyl iodides in the presence of Pd(OAc)2 as catalyst and Ag2CO3 as base. (C) 2000 Elsevier Science Ltd.

The 2-(N,N-dimethylamino)phenylsulfinyl group as an efficient chiral auxiliary in intramolecular heck reactions

(Matrix presented) The synthesis, reactivity, and stereochemical behavior of differently substituted iodoalkenyl α,β-unsaturated sulfoxides in intramolecular Heck reaction is described. Particularly, the 2-(N,N-dimethylamino)phenylsulfinyl group is demons

EINE NEUE SYNTHESE VON VINBLASTIN-DERIVATEN III. SYNTHESE UND REAKTIONEN VON 21,Nb-SECO-CLEAVAMIN-DERIVATEN ALS VORLAUFER ZU 20'-DEETHYL-20'-DEOXYVINBLASTIN UND (+/-)-16α-METHOXYCARBONYL-20-DEETHYL-15,20-DIHYDROCLEAVAMIN

In a new concept for the synthesis of 20'-deethyl-20'deoxyvinblastine, Nb-seco-cleavamine derivatives 1a,2a are possible precursors.For the synthesis of these compounds the indolizino indoles 8I,II were treated with benzyl chloroformate/aq. sodium